TNO BIBRA International

TNO Pharma is a specialist CRO dedicated to the development of pharmaceuticals. TNO is committed to utilising quality, creativity and entrepreneurship to enable its services to be available to a number of businesses as well as organizations and governments worldwide. Our services include: Consultancy - TNO Pharma provides access to a range of development services with over 700 associates working on discovery to post licensing management; Regulatory - Speed of development of candidate drugs is critical to business. Constructive and early regulatory input is essential to avoid costly disappointments. TNO employs experienced regulatory professionals. We can provide practical unbiased support to shape and to improve the quality of business decisions; Pre-clinical - Established in 1930, TNO Pharma is a full service preclinical CRO. We are able to offer the widest and most innovative portfolio of preclinical services of its kind. The portfolio covers flexible development programmes, pharmacology, toxicology, analytical, drug delivery testing and biotechnology services; Clinical Research - Our Clinical Studies Department has its own dedicated team of doctors, nurses, CRAs, project managers and technical staff all in compliance with the ICH-GCP guideline. Our facilities in south London include a purpose built 24-bed unit, with intensive monitoring facilities, temperature and humidity controlled dermal suite, fully equipped dental suites and catering and recreational amenities. Over the last 10 years the department has completed many Phase I and IIa studies.

Contact Details: Woodmansterne Road Carshalton Surrey SM5 4PH United Kingdom Tel: +44 20 8652 1040 Fax: +44 20 8661 7029 Email: help@tnobibra.com WWW: www.tnobibra.com/

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Recent Publications by TNO BIBRA International:
Monitoring transfer of recombinant and nonrecombinant plasmids between Lactococcus lactis strains and members of the human gastrointestinal microbiota in vivo--impact of donor cell number and diet. AIMS: The generation of data of real relevance to the purported risks of...	6th May, 2003	TNO BIBRA International Ltd, Carshalton, Surrey, UK.	J Appl Microbiol. 2002;93(6):954-64.
Lactic acid bacteria in a changing legislative environment. The benefits of using lactic acid bacteria in the food chain, both through...	14th February, 2003	TNO Bibra International Ltd., Woodmansterne Road, Carshalton, Surrey, SM5	Antonie Van Leeuwenhoek. 2002 Aug;82(1-4):353-60.
Inhibition of zaleplon metabolism by cimetidine in the human liver: in vitro studies with subcellular fractions and precision-cut liver slices. 1. The effect of cimetidine on the metabolism of zaleplon (ZAL) in human...	7th December, 2002	TNO BIBRA International Ltd, Woodmansterne Road, Carshalton, Surrey SM5	Xenobiotica. 2002 Oct;32(10):849-62. DOI Direct Link
Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase. 1. The metabolism of Zaleplon (CL-284,846; ZAL) has been studied in...	7th December, 2002	TNO BIBRA International Ltd, Woodmansterne Road, Carshalton, Surrey SM5	Xenobiotica. 2002 Oct;32(10):835-47. DOI Direct Link

BioNews Results for TNO BIBRA International:
I-Flow Launches Full Line Of ON-Q SilverDressings	Pharmaceutical Business Review:  Sep 17 2009 8:50AM Matching: tno international
EFIC Survey Shows 95% Patients Suffer From Chronic Pain Even After One Year Of Treatment	Pharmaceutical Business Review:  Sep 12 2009 11:09PM Matching: tno international
OSI Systems Signs Partnership Agreement For Ambulatory Blood Pressure Monitoring Software	Pharmaceutical Business Review:  Sep 10 2009 5:35PM Matching: tno international
UCB Selects Cambridge Semantics' Anzo Suite	Pharmaceutical Business Review:  Sep 10 2009 9:46AM Matching: tno international
Merck Sharp & Dohme Launches SAFLUTAN In International Market	Pharmaceutical Business Review:  Sep 5 2009 1:57AM Matching: tno international
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