Recent Publications by TransForm Pharmaceuticals Incorporated: |
Solvent effects on the AIBN forced degradation of cumene: Implications for forced degradation practices.
Solvent effects on the AIBN and ACVA forced degradation of cumene are... | 16th July, 2008
| Transform Pharmaceuticals, Inc., Lexington, Massachusetts 02421.
| J Pharm Sci. 2008 Jul 11.
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A high-throughput approach towards a novel formulation of fenofibrate in omega-3 oil.
A novel lipid formulation containing fenofibrate in omega-3 oil was... | 1st July, 2008
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington, MA 02421,
| Eur J Pharm Sci. 2008 Apr 23;33(4-5):351-60. Epub 2008 Jan 21.
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Combined use of crystalline salt forms and precipitation inhibitors to improve oral absorption of celecoxib from solid oral formulations.
Biopharmaceutical evaluation of crystalline celecoxib salts in novel solid... | 10th November, 2007
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington,
| J Pharm Sci. 2007 Oct;96(10):2686-702.
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Performance comparison of a co-crystal of carbamazepine with marketed product.
The carbamazepine: saccharin co-crystal (1) was studied in terms of a... | 12th September, 2007
| TransForm Pharmaceuticals, Inc., Lexington, MA 02421, USA.
| Eur J Pharm Biopharm. 2007 Aug;67(1):112-9. Epub 2006 Dec 28.
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Celecoxib:nicotinamide dissociation: using excipients to capture the cocrystal's potential.
The cocrystal of celecoxib and nicotinamide (Cel:Nic) was crystallized... | 19th August, 2007
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington,
| Mol Pharm. 2007 May-Jun;4(3):386-400. Epub 2007 May 12.
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Hydrates and solid-state reactivity: a survey of beta-lactam antibiotics.
Crystalline hydrates of hydrolytically susceptible pharmaceuticals are... | 15th June, 2007
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington,
| J Pharm Sci. 2007 May;96(5):1090-9.
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Expanding the scope of crystal form evaluation in pharmaceutical science.
The commentary seeks to provide a brief history and perspective on the... | 21st March, 2007
| TransForm Pharmaceuticals Inc. Lexington, MA 02421, USA.
| J Pharm Pharm Sci. 2006;9(3):317-26.
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Combination of automated high throughput platforms, flow cytometry, and hierarchical clustering to detect cell state.
BACKGROUND: This study examined whether hierarchical clustering could be... | 7th March, 2007
| Transform Pharmaceuticals, Incorporated, A Unit of Johnson & Johnson, 29
| Cytometry A. 2007 Jan;71(1):16-27.
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Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?
The evolution of crystal engineering into a form of supramolecular... | 30th September, 2005
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington, MA 02421,
| Chem Commun (Camb). 2004 Sep 7;(17):1889-96. Epub 2004 Aug 5.
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A novel, lipid-free nanodispersion formulation of propofol and its characterization.
PURPOSE: Propofol is a widely used anesthetic agent with highly desirable... | 10th August, 2005
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington,
| Pharm Res. 2005 Mar;22(3):356-61.
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Drugs as materials: valuing physical form in drug discovery.
Traditionally, potency and selectivity (and to some extent metabolism)... | 16th December, 2004
| TransForm Pharmaceuticals Inc., 29 Hartwell Avenue, Lexington,
| Nat Rev Drug Discov. 2004 Nov;3(11):926-34.
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High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids.
The concepts of high-throughput (HT) screening and combinatorial synthesis... | 27th October, 2004
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington, MA 02421,
| Adv Drug Deliv Rev. 2004 Feb 23;56(3):275-300.
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A high-throughput combinatorial approach for the discovery of a cremophor EL-free paclitaxel formulation.
PURPOSE: The purpose of this work was to replace Cremophor-EL in the... | 28th May, 2004
| TransForm Pharmaceuticals, Inc. 29 Hartwell Avenue, Lexington,
| Pharm Res. 2003 Aug;20(8):1302-8.
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Crystal engineering of novel cocrystals of a triazole drug with 1,4-dicarboxylic acids.
Cocrystals of the poorly soluble antifungal drug cis-itraconazole (1) with... | 20th August, 2003
| Transform Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington,
| J Am Chem Soc. 2003 Jul 16;125(28):8456-7.
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Elucidation of crystal form diversity of the HIV protease inhibitor ritonavir by high-throughput crystallization.
Pharmaceutical compounds are molecular solids that frequently exhibit... | 14th May, 2003
| TransForm Pharmaceuticals, Inc., 29 Hartwell Avenue, Lexington, MA 02421,
| Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2180-4. Epub 2003 Feb 25.
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