Recent Publications by Transformation Research: |
p53 Family isoforms.
p63, p73 and p53 are transcription factors members of the p53 gene family... | 19th March, 2008
| University of Dundee, Ninewells Hospital, Department of Surgery, CR-UK
| Curr Pharm Biotechnol. 2007 Dec;8(6):332-6.
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p53 and its isoforms in cancer.
p53, p63 and p73 are members of the p53 gene family involved in... | 3rd October, 2007
| Inserm European Associated Laboratory, Department of Surgery and Molecular
| Br J Cancer. 2007 Aug 6;97(3):277-82. Epub 2007 Jul 17.
DOI Direct Link |
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.
p63, p73 and p53 compose a family of transcription factors involved in... | 30th June, 2007
| Department of Surgery and Molecular Oncology, University of Dundee,
| Cell Death Differ. 2006 Jun;13(6):962-72.
DOI Direct Link |
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2.
Mdm2 is an E3 ubiquitin ligase that promotes its own ubiquitination and... | 6th April, 2007
| CR-UK Cell Transformation Research Group, Department of Surgery and
| EMBO J. 2007 Feb 21;26(4):976-86. Epub 2007 Feb 8.
DOI Direct Link |
Recombinant expression of maize nucleotide excision repair protein Rad23 in Escherichia coli.
Nucleotide excision is a highly conserved DNA repair pathway for... | 4th November, 2005
| Gene Discovery and Modification Laboratory, Department of Transformation
| Protein Expr Purif. 2005 Jun;41(2):287-97.
DOI Direct Link |
p53 isoforms can regulate p53 transcriptional activity.
The recently discovered p53-related genes, p73 and p63, express multiple... | 20th October, 2005
| Department of Surgery, Cancer Research-UK Cell Transformation Research
| Genes Dev. 2005 Sep 15;19(18):2122-37. Epub 2005 Aug 30.
DOI Direct Link |
p14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicase.
Here we demonstrate a novel p53-independent interaction between the... | 8th February, 2005
| CR-UK Cell Transformation Research Group, Department of Surgery and
| J Biol Chem. 2004 Nov 26;279(48):50157-66. Epub 2004 Sep 7.
DOI Direct Link |
Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo.
p53 levels are regulated by ubiquitination and 26 S proteasome-mediated... | 16th November, 2004
| Cancer Research UK, Cell Transformation Research Group, Department of
| J Biol Chem. 2004 Oct 1;279(40):42169-81. Epub 2004 Jul 26.
DOI Direct Link |
T-DNA recombination and replication in maize cells.
T-DNA recombination and replication was analyzed in 'black mexican sweet'... | 8th November, 2003
| Transformation Research, Pioneer Hi-Bred International Inc., Johnston, IA
| Plant J. 2003 Jan;33(1):149-59.
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Site-specific recombination for genetic engineering in plants.
Site-specific recombination has been developed into a genetic engineering... | 17th September, 2003
| Transformation Research, Pioneer Hi-Bred International Inc., 7300 NW 62nd
| Plant Cell Rep. 2003 Jun;21(10):925-32. Epub 2003 Apr 26.
DOI Direct Link |
