Transformation Research

Contact Details: MA United States of America Tel: 617 783 4124 Fax: Email:

Recent Publications by Transformation Research:
Targeting the ubiquitin-proteasome system to activate wild-type p53 for cancer therapy. Ubiquitination plays a key role in regulating the tumour suppressor p53....	10th November, 2009	CR-UK Cell Transformation Research Group, Department of Surgery and	Semin Cancer Biol. 2009 Nov 6. DOI Direct Link
MdmX is a substrate for the deubiquitinating enzyme USP2a. It has previously been shown that ubiquitin-specific protease 2a (USP2a)...	20th October, 2009	CR-UK Cell Transformation Research Group, Division of Molecular Medicine,	Oncogene. 2009 Oct 19. DOI Direct Link
Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53. Both p53 and its repressor Mdm2 are subject to ubiquitination and...	14th April, 2009	CR-UK Cell Transformation Research Group, Department of Surgery and	J Biol Chem. 2009 Feb 20;284(8):5030-41. Epub 2008 Dec 19. DOI Direct Link
p53 Family isoforms. p63, p73 and p53 are transcription factors members of the p53 gene family...	19th March, 2008	University of Dundee, Ninewells Hospital, Department of Surgery, CR-UK	Curr Pharm Biotechnol. 2007 Dec;8(6):332-6.
p53 and its isoforms in cancer. p53, p63 and p73 are members of the p53 gene family involved in...	3rd October, 2007	Inserm European Associated Laboratory, Department of Surgery and Molecular	Br J Cancer. 2007 Aug 6;97(3):277-82. Epub 2007 Jul 17. DOI Direct Link
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BioNews Results for Transformation Research:
Investigators Say CRAF-BRAF Interaction May Explain Nexavars Failure in Melanoma	Genetic Engineering News:  Nov 18 2009 8:19PM Matching: transformation research
Ohr Pharmaceutical (OTCBB: OHRP) CEO Announces Completion of Biotech Transformation With Acquisition of Phase	NewsBlaze:  Nov 11 2009 12:53AM Matching: transformation research
Ohr Pharmaceutical (OTCBB: OHRP) CEO Announces Completion of Biotech Transformation With Acquisition of Phase	Pharmacy Choice:  Nov 10 2009 9:29PM Matching: transformation research
Ohr Pharmaceutical (OTCBB: OHRP) CEO Announces Completion of Biotech Transformation With Acquisition of Phase	Yahoo! Canada:  Nov 10 2009 2:14PM Matching: transformation research
Ohr Pharmaceutical (OTCBB: OHRP) CEO Announces Completion of Biotech Transformation With Acquisition of Phase	Marketwire via Yahoo!:  Nov 10 2009 2:38PM Matching: transformation research
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