TranXenoGen

TranXenoGen is developing transgenic technologiesfor the production of transgenic animals, including

a non-viral method for the transfection of large transgenes

into chicken eggs (Direct-Egg Transfection). The goal is

transgenic chickens that express the recombinant protein

in the albumin fraction of their eggs.



TranXenoGen is also developing a technology (Gene-Testes

Transfection), designed to be applicable in many species of

animals. The technology targets transfection of a transgene

into the male animal in such a way that the male animal will

produce transgenic sperm. Consequently, the male can be

easily bred to generate transgenic animals.





TranXenoGen’s R&D projects also include:





Utilizing avian stem cells to improve the flexibility and

effectiveness of the transgenic chicken platform.





Developing of an in-licensed novel human protein,

anti-neoplastic urinary protein, “ANUP”, from Antitumor

Research Products. ANUP is believed to be an anti-

cancer protein, which is effective in treating cervical and

other cancers. TranXenoGen is currently in early stage

development and in-vitro testing of the product. If

successful, future development in animal models and

preclinical testing will commence.

Contact Details: 800 BOSTON TURNPIKE SHREWSBURY MA 01545 United States of America Tel: 508 936 4200 Fax: Email: WWW: www.tranxenogen.com/

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Recent Publications by TranXenoGen:
A potential antitumor peptide therapeutic derived from antineoplastic urinary protein. New therapies in cancer treatment are focusing on multifaceted approaches...	19th February, 2005	TranXenoGen Inc., Technology Development, 800 Boston Turnpike, Shrewsbury,	Peptides. 2004 Apr;25(4):543-9. DOI Direct Link

Press Releases on TranXenoGen:
PwC BioScience Index & Share League September - October 2002	1st November, 2002	Pwc	PwC BioScience Index & Share League September - October 2002 The PwC BioScience Index highlights the performance of UK bioscience companies

TranXenoGen Patents:
US Patent No.	Title
7326679	Anticancer peptide compositions
6753457	Nuclear reprogramming using cytoplasmic extract

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