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Xenome Limited

Xenome aims to develop new treatments for pain, particularly intractable pain as experienced by many cancer patients, as well as other neurological conditions for which there is an unmet clinical need, e.g stroke.Xenome has an exclusive license to a collection of molecules and related technologies discovered by the Centre for Drug Design and Development (the Centre) at the University of Queensland (now part of the Institute for Molecular Bioscience). These molecules, know as conotoxins, were isolated from the venom of several species of cone shells collected from the Great Barrier Reef and have been shown to selectively inhibit proteins known as ion-channels. Inhibition of certain ion-channels is known to control various types of pain.

Xenome intends to test naturally occurring contoxins, as well as novel molecules, made chemically in the laboratory, for their pharmacological activity. Potentially useful molecules will then be tested in animal models for pain and other neurological conditions.


Contact Details:
Australia
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www.medica.com.au/




Recent Publications by Xenome Limited:

High-throughput synthesis of conopeptides: a safety-catch linker approach enabling disulfide formation in 96-well format.
Conotoxins exhibit a high degree of selectivity and potency for a range of...
27th September, 2007
Xenome Ltd, 120 Meiers Road, Indooroopilly 4068, Australia. J Pept Sci. 2007 Feb;13(2):133-41.
DOI Direct Link
Taxonomy of Australian Funnel-web spiders using rp-HPLC/ESI-MS profiling techniques.
The complex nature of venom from spider species offers a unique natural...
30th June, 2006
Xenome Ltd, P.O. Box 6295, St Lucia, Qld 4067, Australia. Toxicon. 2006 May;47(6):614-27. Epub 2006 Mar 22.
DOI Direct Link
Australian funnel-web spider venom analyzed with on-line RP-HPLC techniques.
The complex nature of venom from spider species offers a unique natural...
25th March, 2004
Xenome Ltd., Indooroopilly, Queensland, Australia. Methods Mol Biol. 2004;251:307-22.

Xenome Limited Patents:

US Patent No.Title
7368432 Conotoxin peptides
7326682 Conotoxin peptides

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