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GENFITGenfit is a biopharmaceutical company, listed on Alternext by Euronext™ Paris (ALGFT - FR0004163111) with headquarters in Lille, France and a US subsidiary in Cambridge, Massachusetts.
Through its world-renowned scientific expertise, particularly in the field of nuclear receptors, Genfit’s research efforts are focused on the discovery and development of new treatments mainly in the growing therapeutic areas of Cardiometabolic and Neurodegenerative disorders, such as prediabetes/diabetes, atherosclerosis, dyslipidemia, obesity, and Alzheimer’s. Genfit uses a multi-pronged approach based on early diagnosis, preventive solutions, and therapeutic treatments to address these major public health problems and their unmet medical needs.
Genfit has an original business model built on both proprietary internal programs and a strong track record of partner-supported programs and collaborations. This strategy allows the company to efficiently manage the risks associated with the internal programs, and at the same time build value for its shareholders. Genfit, on its own or in collaboration with its major pharmaceutical partners, has thus created a rich and diversified pipeline of drug candidates in pre-clinical and clinical development, as well as a broad intellectual property portfolio.
Genfit’s strong portfolio of therapeutic products, tools, and clinical biomarkers, together with its scientific expertise, have made the Company into a European biotechnology leader.
| Contact Details: |
| Parc Eurasanté – Lille Métropole 885, avenue Eugène Avinée |
| LOOS |
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| 59120 |
| France |
| Tel: | +33 (0)3 20 16 40 00 |
| Fax: | +33 (0)3 20 16 40 01 |
| Email: | contact@genfit.com |
| WWW: | www.GENFIT.com
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Recent Publications by GENFIT: |  |
On the central mechanism underlying ghrelin's chronic pro-obesity effects in rats: new insights from studies exploiting a potent ghrelin receptor antagonist.
In the present study, we explore the central nervous system mechanism... | 26th August, 2009
| Department of Physiology/Endocrinology, Institute of Neuroscience and
| J Neuroendocrinol. 2009 Sep;21(9):777-85.
DOI Direct Link |
Phosphorylation of farnesoid X receptor by protein kinase C promotes its transcriptional activity.
The farnesoid X receptor (FXR, NR1H4) belongs to the nuclear receptor... | 12th June, 2009
| GENFIT, Loos-Lez-Lille, France.
| Mol Endocrinol. 2008 Nov;22(11):2433-47. Epub 2008 Aug 28.
DOI Direct Link |
Safety issues and prospects for future generations of PPAR modulators.
Because of their wide range of actions on glucose homeostasis, lipid... | 5th October, 2007
| Genfit, F-59006 Loos, France.
| Biochim Biophys Acta. 2007 Aug;1771(8):1065-81. Epub 2007 Feb 24.
DOI Direct Link |
Farnesoid X receptor represses hepatic lipase gene expression.
The farnesoid X receptor (FXR) is a nuclear receptor that regulates gene... | 22nd April, 2005
| GENFIT, Parc Eurasante, Loos, France.
| J Lipid Res. 2004 Nov;45(11):2110-5. Epub 2004 Sep 1.
DOI Direct Link |
The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c.
Alterations in the expression of the recently discovered apolipoprotein A5... | 16th December, 2004
| Departement d'Atherosclerose, UR545 INSERM, Institut Pasteur de Lille and
| J Biol Chem. 2004 Oct 29;279(44):45462-9. Epub 2004 Aug 17.
DOI Direct Link |
→View more GENFIT research publications. |
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