Recent Publications by Babraham Institute: |
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of E.coli or S.aureus is regulated by Class III but not Class I or II PI3Ks.
Phagocytosis and activation of the NADPH oxidase are important mechanisms... | 30th August, 2008
| Inositide Laboratory, Babraham Institute, Cambridge, United Kingdom.
| Blood. 2008 Aug 28.
DOI Direct Link |
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum.
Autophagy is the engulfment of cytosol and organelles by double-membrane... | 30th August, 2008
| Signalling Programme, Babraham Institute, Babraham, Cambridge, England,
| J Cell Biol. 2008 Aug 25;182(4):685-701.
DOI Direct Link |
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.
DNA methylation patterns are reprogrammed in primordial germ cells and in... | 30th August, 2008
| Laboratory of Developmental Genetics and Imprinting, The Babraham
| PLoS Genet. 2008 Jun 27;4(6):e1000116.
DOI Direct Link |
Censoring of autoreactive B cell development by the pre-B cell receptor.
Antibody diversity occurs randomly as B cells recombine their... | 14th August, 2008
| Laboratory of Lymphocyte Signalling and Development, Babraham Institute,
| Science. 2008 Aug 1;321(5889):696-9. Epub 2008 Jun 19.
DOI Direct Link |
Calcium Phosphate Crystals Induce Cell Death in Human Vascular Smooth Muscle Cells. A Potential Mechanism in Atherosclerotic Plaque Destabilization.
Vascular calcification is associated with an increased risk of myocardial... | 2nd August, 2008
| Division of Cardiovascular Medicine, University of Cambridge,
| Circ Res. 2008 Jul 31.
DOI Direct Link |
ERK1/2 and p38 cooperate to delay progression through G1 by promoting cyclin D1 protein turnover.
The conditional kinase DeltaMEKK3:ER allows activation of JNK, p38 and... | 31st July, 2008
| Laboratory of Molecular Signalling, The Babraham Institute, Babraham
| Cell Signal. 2008 Jul 10.
DOI Direct Link |
Interchromosomal huddle kickstarts antiviral defense.
Long-distance chromosomal interactions are emerging as a potential... | 26th July, 2008
| The Babraham Institute, Laboratory of Chromatin and Gene Expression,
| Cell. 2008 Jul 11;134(1):14-6.
DOI Direct Link |
How chromatin remodelling allows shuffling of immunoglobulin heavy chain genes.
Cellular identity is determined by the switching on and off of... | 18th July, 2008
| Laboratory of Chromatin and Gene Expression, Babraham Institute, Babraham
| Mol Biosyst. 2008 Aug;4(8):790-8. Epub 2008 May 14.
DOI Direct Link |
Protein arrays: issues to be addressed.
Protein arrays are fast becoming established as a means to monitor protein... | 17th July, 2008
| Chairman ESF Programme in Integrated Approaches to Functional Genomics The
| Comp Funct Genomics. 2001;2(5):298-300.
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Functional genomics and disease in 2003.
Protein arrays are fast becoming established as a means to monitor protein... | 17th July, 2008
| ESF Programme in Integrated Approaches to Functional Genomics The Babraham
| Comp Funct Genomics. 2003;4(5):516-7.
DOI Direct Link |
Production of protein arrays by cell-free systems.
Protein arrays make possible the functional screening of large numbers of... | 2nd July, 2008
| Technology Research Group, The Babraham Institute, Cambridge, UK.
| Methods Mol Biol. 2008;484:207-15.
DOI Direct Link |
Selection of recombinant antibodies by eukaryotic ribosome display.
Ribosome display is a powerful method for selection of single-chain... | 2nd July, 2008
| Technology Research Group, The Babraham Institute, Cambridge, UK.
| Methods Mol Biol. 2008;484:193-205.
DOI Direct Link |
Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians.
Comparisons between eutherians and marsupials suggest limited conservation... | 1st July, 2008
| The Babraham Institute, Laboratory of Developmental Genetics and
| Nat Genet. 2008 Aug;40(8):971-6. Epub 2008 Jun 29.
DOI Direct Link |
Removal of the BiP-retention domain in Cmicro permits surface deposition and developmental progression without L-chain.
Nascent, full length, immunoglobulin (Ig) heavy (H)-chains are... | 1st July, 2008
| The Babraham Institute, Babraham, Cambridge CB22 3AT, United Kingdom.
| Mol Immunol. 2008 Aug;45(13):3573-9. Epub 2008 Jun 26.
DOI Direct Link |
Increased Cdx protein dose effects upon axial patterning in transgenic lines of mice.
To investigate the link between Cdx protein concentration and axial... | 27th June, 2008
| Department of Development and Genetics, The Babraham Institute, Babraham,
| Development. 2008 Aug;135(15):2511-20. Epub 2008 Jun 25.
DOI Direct Link |
