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BioFocus

BioFocus is a collaborative drug discovery company providing an integrated platform of expertise and technologies in medicinal chemistry and biological screening to the global biopharmaceutical industry. Designed to accelerate clients’ discovery programmes, BioFocus’ products and services are offered on a flexible basis and include diverse or targeted (SoftFocusTM) screening libraries, assay development, high-throughput screening, hit-to-lead optimisation and all associated informatics. Clients have access to propriety technologies such as Predictive Array DesignTM

(a patented library design methodology) and a range of proprietary screening platforms. The company has specialized expertise in Kinase, GPCR and ion-channel targets and offers or is developing opportunities for drug discovery partnerships in these areas. Current partners include Aventis Cropscience, Biovitrum, GlaxoSmithKline, Millennium, Oxford GlycoSciences, Pfizer, Roche and Teijin.


Contact Details:
Chesterford Research Park
Saffron Walden
Essex
CB10 1XL
United Kingdom
Tel:+44 1799 533 500
Fax:+44 1799 531 495
Email:
WWW:

www.biofocus.co.uk/




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Recent Publications by BioFocus:

Recent advances in electrophysiology-based screening technology and the impact upon ion channel discovery research.
Ion channels are recognised as an increasingly tractable class of targets...
25th September, 2009
Ion Channel Biology BioFocus DPI, Saffron Walden, Essex, UK. Methods Mol Biol. 2009;565:187-208.
DOI Direct Link
How large does a compound screening collection need to be?
Increasingly, chemical libraries are being produced which are focused on a...
28th March, 2009
BioFocus DPI, Chesterford Research Park, Saffron Walden, Essex, UK. Comb Chem High Throughput Screen. 2008 Jul;11(6):482-93.
Protein structure prediction.
Protein structure prediction has matured over the past few years to the...
11th October, 2008
Biofocus DPI, London, United Kingdom. Methods Mol Biol. 2008;453:33-85.
DOI Direct Link
Use of FLIPR membrane potential dyes for validation of high-throughput screening with the FLIPR and microARCS technologies: identification of ion channel modulators acting on the GABA(A) receptor.
Fluorometric imaging plate reader (FLIPR) membrane potential dyes...
18th September, 2008
Biofocus DPI AG, Allschwil, Switzerland. J Biomol Screen. 2008 Mar;13(3):218-28. Epub 2008 Feb 12.
DOI Direct Link
Automatic QSAR modeling of ADME properties: blood-brain barrier penetration and aqueous solubility.
In this article, we present an automatic model generation process for...
6th August, 2008
BioFocus DPI Ltd., Darwin Building, Chesterford Research Park, Saffron J Comput Aided Mol Des. 2008 Jun-Jul;22(6-7):431-40. Epub 2008 Feb 14.
DOI Direct Link

View more BioFocus research publications.

Press Releases on BioFocus:

BioPortfolio Logo
Cellectricon and BioFocus DPI Advance High Throughput ion Channel Drug Discovery 27th April, 2009
GOTHENBURG, Sweden, April 27 /PRNewswire/ -- Cellectricon, a leading provider of automated screening solutions for drug discovery, today announced its collaboration with BioFocus DPI, a contract
SENEXIS ENTERS INTO A COLLABORATION WITH BIOFOCUS TO DEVELOP NOVEL “SMALL 1st November, 2002 Senexis
SENEXIS ENTERS INTO A COLLABORATION WITH BIOFOCUS TO DEVELOP NOVEL “SMALL MOLECULE” DRUGS FOR THE TREATMENT OF ALZHEIMER’S DISEASE BioFocus medicinal
TheraSci and BioFocus enter Drug Discovery Collaboration 1st October, 2002 Therasci
  TheraSci and BioFocus enter Drug Discovery Collaboration 
Therasci and Xenome enter nervous system drug discovery collaboration 1st January, 1970 Therasci
  Therasci and Xenome enter nervous system drug discovery collaboration

BioNews Results for BioFocus:

Galapagos Business Update
RBC Dain Rauscher:  Nov 13 2009 9:43AM Matching: biofocus
Galapagos third quarter 2009 financial results in line with management expectations
News-Medical.Net:  Nov 13 2009 12:32PM Matching: biofocus
Galapagos Business Update
Individual.com:  Nov 13 2009 7:11AM Matching: biofocus
Appointments update
Pharmafocus:  Nov 3 2009 2:33PM Matching: biofocus
Appointments update
Pharmafocus:  Nov 3 2009 2:33PM Matching: biofocus
Promote your company here: BioNewsCast - Press Release Distribution

View more BioFocus news.

BioFocus Patents:

US Patent No.Title
6528252 Methods for identifying a protease inhibitor
6506557 Methods and compositions for identifying a protease
6387686 Methods and compositions for identifying a polynucleotide encoding a protease

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