Agennix

Agennix is a privately held biotechnology company whose lead molecule, Talactoferrin Alfa (talactoferrin; TLF), is an immunomodulatory protein. Agennix is currently preparing to initiate Phase III development of oral talactoferrin for cancer, and topical talactoferrin gel for wound healing.
Liquid talactoferrin is an oral anti-cancer drug that has shown activity both as monotherapy and in combination with other chemotherapeutic agents. In non-small cell lung cancer (NSCLC), talactoferrin was evaluated in a Phase II, double-blind, placebo-controlled clinical trial where patients received standard first-line chemotherapy combined with either oral talactoferrin or placebo. The trial met its primary endpoint. Talactoferrin improved the relative confirmed response rate by 56% in the intent-to-treat population, and 62% in the prospectively defined evaluable population.

Contact Details: 8 Greenway Plaza, Suite 910 Houston Texas 77046 United States of America Tel: (713) 552-1091 Fax: (713) 552-0795 Email: dduke@agennix.com WWW: www.agennix.com/

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Recent Publications by Agennix:
Talactoferrin stimulates wound healing with modulation of inflammation. BACKGROUND: Inflammation is an acute, early process during normal wound...	15th October, 2008	Agennix Inc.,	J Surg Res. 2008 Oct;149(2):278-86. Epub 2008 Jan 10. DOI Direct Link
Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy. In this work, we investigated the anticancer activity of orally...	28th August, 2004	Agennix, Inc.,	Int J Cancer. 2004 Sep 1;111(3):398-403. DOI Direct Link

Press Releases on Agennix:
Agennix Receives Fast Track Designation From FDA for Talactoferrin in Combination With Sunitinib for Renal Cell Carcinoma	19th May, 2009	Agennix	HOUSTON, May 19 /PRNewswire/ -- Agennix announced today that talactoferrin alfa (talactoferrin) has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the first
Texas Marketing Firm HC&B Named Among Top 60 Healthcare Agencies in U.S.	8th July, 2008	HC&B Healthcare Communications	AUSTIN, Texas, July 8 /PRNewswire/ -- HC&B Healthcare Communications, the leading healthcare marketing agency in the Southwest, has been ranked one of the top 60 healthcare firms in the nation

BioNews Results for Agennix:
Agennix Completes GPC Merger, but Badly Needs Cash Infusion	Therapeutics Daily:  Nov 11 2009 12:48AM Matching: agennix
GPC Biotech merges with Agennix	TradingMarkets:  Nov 9 2009 6:27PM Matching: agennix
GPC Biotech merges with Agennix Deal In Brief	Quote.com Germany:  Nov 9 2009 10:43PM Matching: agennix
Agennix AG Shares Begin Trading on Frankfurt Stock Exchange	Therapeutics Daily:  Nov 6 2009 11:18AM Matching: agennix
Merger of GPC Biotech AG Into Agennix AG Closes	Genetic Engineering News:  Nov 5 2009 4:59PM Matching: agennix
Promote your company here: BioNewsCast - Press Release Distribution	→View more Agennix news.

Agennix Clinical Trials:
Safety and Efficacy of Talactoferrin in Previously Treated Patients With Non-small Cell Lung Cancer

Agennix Patents:
US Patent No.	Title
7592306	Lactoferrin as an agent in the prevention of organ transplant rejection and graft-versus-host-disease
6080559	Expression of processed recombinant lactoferrin and lactoferrin polypeptide fragments from a fusion product in Aspergillus
6399570	Antimicrobial/endotoxin neutralizing polypeptide
7026295	Lactoferrin in the reduction of circulating cholesterol, vascular inflammation, atherosclerosis and cardiovascular disease
7034126	Lactoferrin in the treatment of diabetes mellitus
→View more Agennix patents.

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