Ambit Biosciences

Ambit Biosciences is a privately-held biopharmaceutical company engaged in the discovery and development of small-molecule kinase inhibitors for the treatment of cancer.
With more than 500 distinct kinases identified and over 30 kinase inhibitors in clinical trials or FDA approved, this important class of proteins is a rich area for therapeutic drug development. And Ambit Biosciences has the technology, the expertise and the vision to succeed in the kinase space.

Contact Details: 4215 Sorrento Valley Blvd. San Diego California 92121 United States of America Tel: 858-334-2100 Fax: 858-334-2199 Email: tlyons@ambitbio.com. WWW: www.ambitbio.com/

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Recent Publications by Ambit Biosciences:
Stearoyl-CoA desaturase inhibitors: update on patented compounds. BACKGROUND: Stearoyl-CoA desaturase 1 (SCD1) has been implicated as a...	27th October, 2009	Ambit Biosciences, 4215 Sorrento Valley Blvd, San Diego, CA 92121, USA.	Expert Opin Ther Pat. 2009 Sep;19(9):1169-91. DOI Direct Link
AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML). Activating mutations in the receptor tyrosine kinase FLT3 are present in...	6th August, 2009	Ambit Biosciences,	Blood. 2009 Oct 1;114(14):2984-92. Epub 2009 Aug 4. DOI Direct Link
Arylcarboxyamino-substituted diaryl ureas as potent and selective FLT3 inhibitors. A series of diaryl ureas with an amide substitution at the 4-position was...	4th August, 2009	Ambit Biosciences Inc., 4215 Sorrento Valley Boulevard, San Diego, CA	Bioorg Med Chem Lett. 2009 Sep 1;19(17):5182-5. Epub 2009 Jul 9. DOI Direct Link
Azacycloalkane derivatives as inhibitors of delta-9 stearoyl-coenzyme A desaturase. BACKGROUND: Extensive target validation has supported a controlling role...	1st August, 2009	Ambit Biosciences, 4215 Sorrento Valley Blvd, San Diego, CA 92121, USA.	Expert Opin Ther Pat. 2009 Jun;19(6):885-91. DOI Direct Link
Kinase inhibitors for the treatment of inflammatory and autoimmune disorders. Drugs targeting inhibition of kinases for the treatment of inflammation...	24th June, 2008	Ambit Biosciences, 4215 Sorrento Valley Boulevard, San Diego, CA, 92121,	Purinergic Signal. 2009 Mar;5(1):107-15. Epub 2008 Jun 21. DOI Direct Link
→View more Ambit Biosciences research publications.

Press Releases on Ambit Biosciences:
Rib-X Pharmaceuticals, Inc. Appoints Dr. Joseph Amprey of MedImmune Ventures to Board of Directors	3rd September, 2008	Rib-X Pharmaceuticals, Inc.	NEW HAVEN, Conn., Sept. 3 /PRNewswire/ -- Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery and development of novel

Ambit Biosciences Clinical Trials:
A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status

Ambit Biosciences Patents:
US Patent No.	Title
7323490	Pyrrole compounds and uses thereof
7112435	Uncoupling of DNA insert propagation and expression of protein for phage display

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