Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME’s principal focus has been on applying its proprietary AMEsystem™ technology platform to the full range of protein therapeutic candidates including antibodies, cytokines, hormones and enzymes to develop novel human biotherapeutic candidates.
Since February 2004, AME has been a wholly-owned subsidiary of Eli Lilly and Company and is an integral part of Lilly’s research organization. Lilly, a leading innovation-driven corporation is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs.
While geographically separate, AME works closely with Lilly colleagues in Indianapolis and around the world, sharing a corporate legacy of integrity and commitment to quality that spans more than a century.
| Contact Details: |
| 3520 Dunhill street |
| San Diego |
| California |
| 92121 |
| United States of America |
| Tel: | 858.597.4990 |
| Fax: | 858.597.4950 |
| Email: | |
| WWW: | www.ame.biz/
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Recent Publications by Applied Molecular Evolution: |  |
Peptide membranes in chemical evolution.
Simple surfactants achieve remarkable long-range order in aqueous... | 3rd November, 2009
| Center for Fundamental and Applied Molecular Evolution and the Center for
| Curr Opin Chem Biol. 2009 Oct 28.
DOI Direct Link |
Templating molecular arrays in amyloid's cross-beta grooves.
Amyloid fibers, independent of primary amino acid sequence, share a common... | 15th October, 2009
| Center for Fundamental and Applied Molecular Evolution, and Department of
| J Am Chem Soc. 2009 Jul 29;131(29):10165-72.
DOI Direct Link |
The molecular language of semagenesis.
Semagenesis, the process of signal generation, is a novel signaling... | 26th August, 2009
| Center for Fundamental and Applied Molecular Evolution; Emory University
| Plant Signal Behav. 2008 Aug;3(8):560-1.
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How evolving enzymes can beat the heat and avoid defeat.
Semagenesis, the process of signal generation, is a novel signaling... | 8th August, 2009
| Department of Biochemistry, Center for Fundamental and Applied Molecular
| Nat Chem Biol. 2009 Aug;5(8):538-9.
DOI Direct Link |
2'-deoxy-1-methylpseudocytidine, a stable analog of 2'-deoxy-5-methylisocytidine.
2'-deoxy-5-methylisocytidine is widely used in assays to personalize the... | 1st July, 2009
| Westheimer Institute for Science and Technology, Foundation for Applied
| Bioorg Med Chem. 2009 May 15;17(10):3728-32. Epub 2009 Mar 27.
DOI Direct Link |
→View more Applied Molecular Evolution research publications. |
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