Applied Molecular Evolution (AME) is a leader in applying directed molecular evolution to improve healthcare by discovering, optimizing and developing human biotherapeutics. Since its inception, AME’s principal focus has been on applying its proprietary AMEsystem™ technology platform to the full range of protein therapeutic candidates including antibodies, cytokines, hormones and enzymes to develop novel human biotherapeutic candidates.
Since February 2004, AME has been a wholly-owned subsidiary of Eli Lilly and Company and is an integral part of Lilly’s research organization. Lilly, a leading innovation-driven corporation is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs.
While geographically separate, AME works closely with Lilly colleagues in Indianapolis and around the world, sharing a corporate legacy of integrity and commitment to quality that spans more than a century.
| Contact Details: |
| 3520 Dunhill street |
| San Diego |
| California |
| 92121 |
| United States of America |
| Tel: | 858.597.4990 |
| Fax: | 858.597.4950 |
| Email: | |
| WWW: | www.ame.biz/

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Recent Publications by Applied Molecular Evolution: |  |
Cross-strand pairing and amyloid assembly.
Amino acid cross-strand pairing interactions along a beta-sheet surface... | 4th October, 2008
| Center for Fundamental and Applied Molecular Evolution, Department of
| Biochemistry. 2008 Sep 23;47(38):10018-26. Epub 2008 Aug 30.
DOI Direct Link |
Capturing the VirA/VirG TCS of Agrobacterium tumefaciens.
Two-component systems (TCS) regulate pathogenic commitment in many... | 17th September, 2008
| Center for Fundamental and Applied Molecular Evolution, Department of
| Adv Exp Med Biol. 2008;631:161-77.
|
Synthesis of novel bicyclic nucleosides with 3,6-anhydro sugar moiety.
Based on the biological importance of conformationally restricted... | 13th September, 2008
| Foundation for Applied Molecular Evolution, Gainesville, Florida 32601,
| Nucleosides Nucleotides Nucleic Acids. 2008 Oct;27(10):1097-106.
DOI Direct Link |
Synthetic biology for improved personalized medicine.
Tools to re-sequence the genomes of individual patients having well... | 9th September, 2008
| Foundation for Applied Molecular Evolution, 1115 NW 4 Street, Gainesville,
| Nucleic Acids Symp Ser (Oxf). 2008;(52):243-4.
DOI Direct Link |
Self-Avoiding Molecular Recognition Systems (SAMRS).
Reported here is a "Self-Avoiding Molecular Recognition Systems" (SAMRS),... | 9th September, 2008
| Foundation for Applied Molecular Evolution, 1115 NW 4 Street, Gainesville,
| Nucleic Acids Symp Ser (Oxf). 2008;(52):129-30.
DOI Direct Link |
→View more Applied Molecular Evolution research publications. |
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Applied Molecular Evolution