Axiogenesis AG is an innovative biotech company with expertise in applied stem cell technology.
Using state-of-the-art methods in cellular and molecular biology as well as functional analytics Axiogenesis develops novel techniques in diagnosis and therapy of economically and medically relevant diseases. Basis of Axiogenesis' daily work are genetically modified mouse embryonic stem cells. Our assay systems can be used for screening of new compounds (chemicals, drugs, consumables) on the developing embryo and on regular differentiated functional tissue.
Beside the identification of toxic and teratogenic compounds our assays are also used to search for tissue-specific signaling molecules ("small molecules") for the development of a new generation of drugs.
Further development of our cell-based assays to high throughput screening allows efficient testing of new compounds on important tissues (heart, neurons, vessels, cartilage) at low cost rates. Furthermore, using Axiogenesis' assay systems, the amount of animal testing in toxicology and drug development can be markedly reduced.
| Contact Details: |
| Joseph-Stelzmann-Str. 50 |
| Cologne |
| |
| 50931 |
| Germany |
| Tel: | 49 (0)221 - 478 7676 |
| Fax: | 49 (0)221 - 478 7782 |
| Email: | info@axioGENESIS.com |
| WWW: | www.axiogenesis.com/
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Recent Publications by Axiogenesis AG: |  |
Preclinical assessment of cardiac toxicity.
The exact prediction of the clinical behavior of drugs represents one of... | 17th December, 2008
| Axiogenesis AG, Nattermann Allee 1, 50829 Cologne, Germany.
| Drug Discov Today. 2008 Aug;13(15-16):702-7. Epub 2008 Jul 24.
DOI Direct Link |
Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium.
Cellular cardiomyoplasty is an attractive option for the treatment of... | 14th December, 2006
| Axiogenesis AG,
| J Exp Med. 2006 Oct 2;203(10):2315-27. Epub 2006 Sep 5.
DOI Direct Link |
Identification and characterization of embryonic stem cell-derived pacemaker and atrial cardiomyocytes.
The aim of this study was to identify and functionally characterize... | 15th December, 2005
| Axiogenesis
| FASEB J. 2005 Apr;19(6):577-9. Epub 2005 Jan 19.
DOI Direct Link |
In vitro embryotoxicity assessment with dental restorative materials.
OBJECTIVES: Resin (co)monomers may be released from restorative dental... | 16th March, 2005
| Axiogenesis AG, Joseph-Stelzmann-Str. 50, 50931 Koln, Germany.
| J Dent. 2005 Jan;33(1):49-55.
DOI Direct Link |
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