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Biotica Technology LimitedBiotica Technology Limited is a privately held biotechnology company focused on the discovery of novel biopharmaceuticals through the targeted alteration of biosynthetic pathways producing natural products. Its proprietary platform technologies enable both the specific and combinatorial biosynthesis of bioactive polyketides, a particularly diverse class of natural products that have proven to be a rich source of commercially significant pharmaceuticals and agricultural chemicals. Biotica is applying its technologies to the discovery of novel polyketide-derived pharmaceuticals within its therapeutic focus on cancer and other proliferative diseases. Biotica has identified lead molecules addressing specific targets within its chosen focus areas and is applying its technologies in exploratory research to optimise those leads.
| Contact Details: |
| 181A Huntingdon Road |
| Cambridge |
| Cambridgeshire |
| CB3 ODJ |
| United Kingdom |
| Tel: | +44 (0) 1223 276 904 |
| Fax: | +44 (0) 1223 276 904 |
| Email: | info@biotica.co.uk |
| WWW: | www.biotica.co.uk/

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Recent Publications by Biotica Technology Limited: |  |
Glycosylation engineering of spinosyn analogues containing an L-olivose moiety.
Biosynthetic genes encoding proteins involved in the first steps of... | 1st July, 2009
| Biotica Technology Ltd, Chesterford Research Park, Cambridge, UK CB10 1XL.
| Org Biomol Chem. 2009 Apr 21;7(8):1705-8. Epub 2009 Mar 12.
DOI Direct Link |
Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
The glycosylation of natural product scaffolds with highly modified... | 5th November, 2008
| Biotica Technology Ltd, Chesterford Research Park, Little Chesterford,
| Org Biomol Chem. 2008 Sep 21;6(18):3315-27. Epub 2008 Jul 28.
DOI Direct Link |
Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
A biosynthetic medicinal chemistry approach was applied to the... | 10th October, 2008
| Biotica Technology Limited, Chesterford Research Park, Nr. Saffron Walden,
| J Med Chem. 2008 Sep 25;51(18):5494-7.
DOI Direct Link |
Molecular characterization of macbecin as an Hsp90 inhibitor.
Macbecin compares favorably to geldanamycin as an Hsp90 inhibitor, being... | 10th July, 2008
| Biotica Technology Limited, Chesterford Research Park, Essex CB10 1XL,
| J Med Chem. 2008 May 8;51(9):2853-7. Epub 2008 Mar 22.
DOI Direct Link |
Drug discovery beyond the 'rule-of-five'.
Although a very useful guideline for orally bioavailable small-molecule... | 15th May, 2008
| Biotica Technology Ltd., Chesterford Research Park, Little Chesterford nr
| Curr Opin Biotechnol. 2007 Dec;18(6):478-88. Epub 2007 Nov 26.
DOI Direct Link |
→View more Biotica Technology Limited research publications. |
Press Releases on Biotica Technology Limited:
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| Biotica Strikes Significant Collaboration Deal With GlaxoSmithKline |
12th January, 2009 |
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CAMBRIDGE, England, January 12 /PRNewswire/ -- Biotica Technology Limited, a privately-held biotechnology
company, announces a significant Collaboration and License Agreement with
GlaxoSmithKline to
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| Biotica appoints Dr Mike Hayes as Non-Executive Chairman |
1st January, 1970 |
Biotica |
Biotica
appoints Dr Mike Hayes as Non-Executive Chairman
Cambridge, U.K. - 19 May, 2003 -Biotica
Technology Limited
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| Inpharmatica announces agreement with Biotica Technology to provide
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1st January, 1970 |
Inpharmatica |
Inpharmatica announces
agreement with Biotica Technology to provide comprehensive ADME support to
their natural products programmes
London, UK, April 19, 2004 --
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