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Biotica Technology Ltd.

Biotica Technology Limited ('Biotica', 'the Company') is a privately held UK biotechnology company focused on the discovery of novel polyketide pharmaceuticals through the targeted alteration of polyketide biosynthetic pathways. Its proprietary synthetic biology platforms enable both the specific and combinatorial biosynthesis of bioactive polyketides. Polyketides are a diverse class of natural products that have been a prolific source of commercially significant pharmaceuticals, currently representing worldwide sales in excess of $20 billion pa. The Company applies its technology platform to discover polyketides that are potentially useful therapeutics for the treatment of cancer and other diseases.


Contact Details:
Chesterford Research ParkLittle Chesterford
Nr Saffron Walden
Essex
CB10 1XL
United Kingdom
Tel:44 (0)1799 532936
Fax:44 (0)1799 532932
Email:info@biotica.com
WWW:

www.biotica.co.uk/




Recent Publications by Biotica Technology Ltd.:

Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.
A biosynthetic medicinal chemistry approach was applied to the...
10th October, 2008
Biotica Technology Limited, Chesterford Research Park, Nr. Saffron Walden, J Med Chem. 2008 Sep 25;51(18):5494-7.
DOI Direct Link
Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.
The glycosylation of natural product scaffolds with highly modified...
20th September, 2008
Biotica Technology Ltd, Chesterford Research Park, Little Chesterford, Org Biomol Chem. 2008 Sep 21;6(18):3315-27. Epub 2008 Jul 28.
DOI Direct Link
Molecular characterization of macbecin as an Hsp90 inhibitor.
Macbecin compares favorably to geldanamycin as an Hsp90 inhibitor, being...
10th July, 2008
Biotica Technology Limited, Chesterford Research Park, Essex CB10 1XL, J Med Chem. 2008 May 8;51(9):2853-7. Epub 2008 Mar 22.
DOI Direct Link
Drug discovery beyond the 'rule-of-five'.
Although a very useful guideline for orally bioavailable small-molecule...
15th May, 2008
Biotica Technology Ltd., Chesterford Research Park, Little Chesterford nr Curr Opin Biotechnol. 2007 Dec;18(6):478-88. Epub 2007 Nov 26.
DOI Direct Link
Engineering of the spinosyn PKS: directing starter unit incorporation.
The spinosyns are a family of potent and highly selective insect control...
1st February, 2007
Biotica Technology Limited, Chesterford Research Park, Essex, CB10 1XL, J Nat Prod. 2006 Dec;69(12):1702-10.
DOI Direct Link

View more Biotica Technology Ltd. research publications.

BioNews Results for Biotica Technology Ltd.:

New Drug Delivery for Self-Administration Report now Available
Pharma Live:  Oct 5 2008 10:36PM Matching: technology
GM corn testing for the ACT
Queensland Country Life:  Oct 6 2008 12:51AM Matching: technology
Ablynx Is Awarded ,1.8 Million Grant To Explorenovel Methods For Uses Of Nanobodies
Pharma Live:  Oct 6 2008 12:47AM Matching: technology
GM corn testing for the ACT
Stock Journal:  Oct 6 2008 12:44AM Matching: technology
Luminex Corporation Hosts Sixth Annual Planet xMap Europe 2008 Symposium
Pharma Live:  Oct 5 2008 7:50AM Matching: technology
Promote your company here: BioNewsCast - Press Release Distribution

View more Biotica Technology Ltd. news.

Biotica Technology Ltd. Patents:

US Patent No.Title
7390895 Production of polyketides and other natural products
6437151 Erythromycins and process for their preparation
6960453 Hybrid polyketide synthases combining heterologous loading and extender modules
7001747 Nucleic acid molecules encoding modified polyketide synthases containing polylinkers and uses thereof
7018808 Polyketides and their synthesis and use

View more Biotica Technology Ltd. patents.

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