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BioVex

BioVex is a biotechnology company focused on the development of novel biologics for the treatment of cancer. The Company’s platforms are based on the manipulation of the herpes simplex virus (HSV). BioVex’s lead product candidate, OncoVEXGM-CSF is in a Phase II clinical trial in melanoma and a Phase I/II clinical trial in head and neck cancer. Further trials in other solid tumors are planned for 2006. The Company is based in Cambridge Massachusetts, with an R&D facility in Oxford, UK


Contact Details:
245 First Street Suite 1800
Cambridge
Massachusetts
02142
United States of America
Tel:1 617 444 8445
Fax:1 617 444 8405
Email:gbeynon@biovex.com
WWW:

www.biovex.com/




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Recent Publications by BioVex:

Phase II Clinical Trial of a Granulocyte-Macrophage Colony-Stimulating Factor-Encoding, Second-Generation Oncolytic Herpesvirus in Patients With Unresectable Metastatic Melanoma.
PURPOSE: Treatment options for metastatic melanoma are limited. We...
4th November, 2009
Mary Crowley Cancer Research Centers; Texas Oncology Physicians J Clin Oncol. 2009 Nov 2.
DOI Direct Link
Retrograde viral transduction of cortical pyramidal neurons from the spinal cord.
PURPOSE: The primary motor pathway, the corticospinal tract, is a major...
10th April, 2009
Biovex Ltd, London, UK. Restor Neurol Neurosci. 2008;26(6):509-20.
Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus.
Considerable interest has been focused on inducing RNA interference (RNAi)...
10th September, 2008
BioVex Inc., 34 Commerce Nucleic Acids Res. 2008 Aug;36(14):e86. Epub 2008 Jun 25.
DOI Direct Link
Development of a second-generation oncolytic Herpes simplex virus expressing TNFalpha for cancer therapy.
BACKGROUND: Tumour necrosis factor alpha (TNFalpha) therapy is a promising...
8th June, 2007
Biovex Ltd., 70 Milton Park, Abingdon, Oxon OX14 4RX, UK. J Gene Med. 2007 Feb;9(2):99-106.
DOI Direct Link
Combination of a fusogenic glycoprotein, prodrug activation, and oncolytic herpes simplex virus for enhanced local tumor control.
We have previously developed an oncolytic herpes simplex virus-1 based on...
6th July, 2006
Biovex Inc., Woburn, Massachusetts 01801, USA. Cancer Res. 2006 May 1;66(9):4835-42.
DOI Direct Link

View more BioVex research publications.

Press Releases on BioVex:

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BioVex Completes $70 Million Financing to Conclude Pivotal Study With Its Pioneering Cancer Treatment, OncoVEX (GM-CSF) 10th November, 2009 BioVex
WOBURN, Mass., Nov. 10 /PRNewswire/ -- BioVex Inc, a company developing new generation biologics for the treatment and prevention of cancer and infectious disease, announced today that it has
BioVex Announces Publication of Phase 2 Melanoma Results With OncoVEX (GM-CSF) in the Journal of Clinical Oncology 2nd November, 2009 BioVex Inc
WOBURN, Mass., Nov. 2 /PRNewswire/ -- BioVex Inc, a company developing new generation biologics for the treatment and prevention of cancer and infectious disease, announced today that the data from
BioVex to Report Phase I/II Clinical Trial Results for the Front Line Treatment of Head and Neck Cancer With OncoVEX GM-CSF at the 2009 American Society of Clinical Oncology Meeting 15th May, 2009 BioVex Inc
WOBURN, Mass., May 15 /PRNewswire/ -- BioVex Inc, a company developing next generation biologics for the treatment and prevention of cancer and infectious disease, announced today that the results
BioVex To Announce Updated Survival Data From a Phase II Clinical Study of OncoVEX GM-CSF in Metastatic Melanoma at The 2009 American Society of Clinical Oncology Meeting 15th May, 2009 BioVex Inc
WOBURN, Mass., May 15 /PRNewswire/ -- BioVex Inc, a company developing new generation biologics for the treatment and prevention of cancer and infectious disease, announced today that updated survival
BioVex Commences OncoVEX (GM-CSF) Phase 3 Trial in Metastatic Melanoma 14th April, 2009 BioVex Inc
WOBURN, Mass., April 14 /PRNewswire/ -- BioVex Inc, a company developing next generation biologics for the treatment and prevention of cancer and infectious disease, announced today that its OPTiM

BioNews Results for BioVex:

Trial of a Viral Cancer Therapy
Longevity Meme:  Nov 17 2009 6:52PM Matching: biovex
BioVex Completes $70 Million Financing to Conclude Pivotal Study With Its Pioneering Cancer Treatment, OncoVEX
TickerTech.com:  Nov 12 2009 5:22PM Matching: biovex
BioVex's $70M Series F to Fund Pivotal OncoVex Melanoma Trial
Therapeutics Daily:  Nov 11 2009 3:05AM Matching: biovex
BioVex Completes $70 Million Financing to Conclude Pivotal Study With Its Pioneering Cancer ...
PipelineReview:  Nov 11 2009 1:12AM Matching: biovex
BioVex Completes $70 Million Financing to Conclude Pivotal Study With Its Pioneering Cancer Treatment, OncoVEX (GM-CSF)
SmartBrief:  Nov 11 2009 12:46AM Matching: biovex
Promote your company here: BioNewsCast - Press Release Distribution

View more BioVex news.

BioVex Clinical Trials:

Efficacy and Safety Study of OncoVEXGM-CSF Compared to GM-CSF in Melanoma

BioVex Patents:

US Patent No.Title
7537924 Virus strains
6713067 Herpes viruses for immune modulation
6719982 Mutant herpes simplex viruses and uses thereof
6821753 Replication incompetent herpes viruses for use in gene therapy
7063835 Virus strains

View more BioVex patents.

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