CGI Pharmaceuticals

CGI Pharmaceuticals is dedicated to the discovery and development of breakthrough small molecule kinase inhibitors for a broad range of oncology/angiogenesis and autoimmune/allergic/inflammatory disease indications. The Company’s fully integrated drug discovery infrastructure comprises proprietary discovery biology and chemistry, extensive lead generation capabilities, as well as preclinical and growing clinical development expertise.

Contact Details: 36 East Industrial Road Branford Connecticut 06405 United States of America Tel: (203) 315-1222 Fax: (203) 488-7838 Email: jobs@cgipharma.com WWW: www.cellulargenomics.com/

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Recent Publications by CGI Pharmaceuticals:
Imidazo[1,2-a]pyrazine diaryl ureas: inhibitors of the receptor tyrosine kinase EphB4. Inhibition of receptor tyrosine kinases (RTKs) such as vascular...	3rd November, 2009	Department of Medicinal Chemistry, CGI Pharmaceuticals, Inc., 36 East	Bioorg Med Chem Lett. 2009 Dec 15;19(24):6991-5. Epub 2009 Oct 15. DOI Direct Link
Chemical genetic transcriptional fingerprinting for selectivity profiling of kinase inhibitors. The importance of protein kinases as a major class of drug targets across...	25th April, 2007	CGI Pharmaceuticals, Inc., Branford, CT 06405, USA.	Assay Drug Dev Technol. 2007 Feb;5(1):49-64. DOI Direct Link
Chemical genetic approaches to kinase drug discovery. Chemical genetics is an important approach in biological research that...	18th October, 2005	CGI Pharmaceuticals Inc, 36 East Industrial Road, Branford, CT 06405, USA.	Curr Opin Drug Discov Devel. 2005 Sep;8(5):638-45.

CGI Pharmaceuticals Patents:
US Patent No.	Title
7405295	Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
7393848	Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
7312341	6-aryl-imidazo[1,2-a] pyrazin-8-ylamines, method of making, and method of use thereof
7259164	Certain substituted imidazo[1,2-a]pyrazines, as modulators of kinase activity
7189723	Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
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