Vitae Pharmaceuticals

Vitae Pharmaceuticals is an emerging pharmaceutical company with two compounds in human clinical trials, a broad portfolio of late stage preclinical programs and an underlying pipeline of discovery programs. Vitae's goal is to discover, develop and commercialize innovative new medicines that will be best-in-class for important disease areas, such as cardiovascular diseases, cancer and dermatology.We are focused on the development of compounds for high value, well validated biological targets. In our discovery and development processes, we seek to leverage available existing clinical and / or preclinical knowledge to efficiently and effectively create novel drug candidates that can address clear unmet therapy needs. Vitae's unique product engine combines the drug discovery skills of proven, deeply experienced drug hunters with state-of-the-art proprietary drug design technologies. This integrated and entrepreneurial approach improves the quality and innovativeness of the compounds we discover, while dramatically shortening the time required to bring them to the clinic.We have demonstrated the ability to rapidly advance novel compounds into clinical development, as Vitae now has clinical candidates in three therapeutic areas, two of which are in clinical studies and a pipeline of additional promising compounds.

Contact Details: 502 West Office Center Drive Fort Washington Pennsylvania 19034 United States of America Tel: (215) 461-2000 Fax: (215) 461-2006 Email: contact@vitaepharma.com WWW: www.concurrentpharma.com/

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Recent Publications by Vitae Pharmaceuticals:
Design and optimization of renin inhibitors: Orally bioavailable alkyl amines. Structure-based drug design led to the identification of a novel class of...	2nd September, 2009	Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, PA	Bioorg Med Chem Lett. 2009 Jul 1;19(13):3541-5. Epub 2009 May 5. DOI Direct Link
Purification and characterization of recombinant human renin for X-ray crystallization studies. BACKGROUND: The renin-angiotensin-aldosterone system (RAS) cascade is a...	13th August, 2008	Vitae Pharmaceuticals Inc., Discovery Biology, Fort Washington, PA, 19034,	BMC Biochem. 2008 Jun 26;9:19. DOI Direct Link
Cloning, characterization and site-directed mutagenesis of canine renin. Inhibition of renin has been shown to be successful in managing...	12th June, 2008	Department of Discovery Biology, Vitae Pharmaceuticals Inc., Fort	J Biochem. 2007 Dec;142(6):671-80. Epub 2007 Oct 17. DOI Direct Link
Development of inhibitors of the aspartyl protease renin for the treatment of hypertension. Renin is the rate-limiting enzyme in the renin-angiotensin-aldosterone...	16th September, 2006	Vitae Pharmaceuticals, Discovery Biology, 502 West Office Center Dr. Ft.	Curr Protein Pept Sci. 2006 Jun;7(3):241-54.

Press Releases on Vitae Pharmaceuticals:
From Curiosity to Discovery: Boehringer Ingelheim's Pipeline Update Unveils Novel Investigational Compounds Heralding the Company's Entry Into Type 2 Diabetes	17th October, 2008		INGELHEIM and BIBERACH, Germany, October 17 /PRNewswire/ -- Boehringer Ingelheim announced that patients and physicians may have several innovative type 2 diabetes treatment alternatives available in

BioNews Results for Vitae Pharmaceuticals:
Vitae Pharmaceuticals to Present at Windhover's Annual Therapeutic Area Partnerships Conference	Therapeutics Daily:  Nov 12 2009 5:01AM Matching: vitae pharmaceuticals
Vitae Pharmaceuticals to Present at Windhover's Annual Therapeutic Area Partnerships Conference	FinanzNachrichten.de:  Nov 11 2009 12:46PM Matching: vitae pharmaceuticals
Vitae Pharmaceuticals to Present at Windhover's Annual Therapeutic Area Partnerships Conference	Forbes.com:  Nov 11 2009 12:52PM Matching: vitae pharmaceuticals
Vitae Pharmaceuticals to Present at Windhover's Annual Therapeutic Area Partnerships Conference	RBC Dain Rauscher:  Nov 11 2009 12:50PM Matching: vitae pharmaceuticals
Vitae Pharmaceuticals to Present at Windhover's Annual Therapeutic Area Partnerships Conference	Business Wire via Yahoo!:  Nov 11 2009 12:53PM Matching: vitae pharmaceuticals
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