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DIATOS S.A

Diatos is a biopharmaceutical company founded in 1999 and headquartered in Paris, France with two subsidiaries in Leuven, Belgium and in the San Francisco Bay Area, USA.
Diatos is focused on the research, development and marketing of new versions of existing anti-cancer chemotherapeutic drugs with enhanced tumor targeting or improved biodistribution. Diatos has built its portfolio of drugs and drug candidates through a strategy of license acquisitions as well as an internal research and development activity based on its prodrug technologies, Vectocell® and Tumor-Selective Prodrug (TSP).

The Company’s portfolio includes DaunoXome®, a drug currently marketed for the treatment of Kaposi’s sarcoma and currently being registered for the treatment of AML and two drugs in clinical development for the treatment of various solid tumours, DTS-301 and DTS-201. The portfolio of Diatos also includes drug candidates in the earlier stages of development.


Contact Details:
3-5 Impasse Reille
Paris
F-75014
France
Tel:33 1 53 80 93 40
Fax:33 1 53 80 93 89
Email:contact@diatos.com
WWW:

www.diatos.com/




Recent Publications by DIATOS S.A:

DTS-108, a novel peptidic prodrug of SN38: in vivo efficacy and toxicokinetic studies.
PURPOSE: Irinotecan is a prodrug converted to the active cytotoxic...
25th June, 2008
Diatos S.A., Paris, France. Clin Cancer Res. 2008 Apr 1;14(7):2145-53.
DOI Direct Link
Preclinical toxicity, toxicokinetics, and antitumoral efficacy studies of DTS-201, a tumor-selective peptidic prodrug of doxorubicin.
PURPOSE: There is a clear clinical need for cytotoxic drugs with a lower...
5th June, 2008
Diatos S.A., Paris, France. Clin Cancer Res. 2008 Feb 15;14(4):1258-65.
DOI Direct Link
Improved therapeutic efficacy of doxorubicin through conjugation with a novel peptide drug delivery technology (Vectocell).
Improvement in the therapeutic index of doxorubicin, a cytotoxic molecule,...
20th January, 2007
Diatos S.A., 166 Boulevard du Montparnasse, 75014 Paris, France. J Med Chem. 2006 Nov 16;49(23):6908-16.
DOI Direct Link
Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules.
Short peptide sequences that are able to transport molecules across the...
13th January, 2006
Diatos S.A., 166 Boulevard du Montparnasse, 75014 Paris, France. Biochem J. 2005 Sep 1;390(Pt 2):407-18.
DOI Direct Link

DIATOS S.A Patents:

US Patent No.Title
7544664 Sequences facilitating penetration of a substance of interest
7112562 Insulin conjugates and methods of use thereof
7049286 Insulin conjugates and methods of use thereof

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