Recent Publications by DRL: |
Glucokinase (GCK) and other susceptibility genes for beta-cell dysfunction: the candidate approach.
There are well-documented examples in the literature of where determining... | 4th November, 2008
| Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology
| Biochem Soc Trans. 2008 Jun;36(Pt 3):306-11.
DOI Direct Link |
Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome.
AIMS/HYPOTHESIS: Variants in the fat-mass and obesity-associated gene... | 22nd October, 2008
| Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill
| Diabetologia. 2008 Jul;51(7):1153-8. Epub 2008 May 14.
DOI Direct Link |
Genome-wide association studies: potential next steps on a genetic journey.
Genome-wide association studies have successfully identified numerous loci... | 15th October, 2008
| Oxford Centre for Diabetes, Endocrinology and Metabolism, University of
| Hum Mol Genet. 2008 Oct 15;17(R2):R156-65.
DOI Direct Link |
Speech technology-based assessment of phoneme intelligibility in dysarthria.
Background: Currently, clinicians mainly rely on perceptual judgements to... | 30th September, 2008
| DRL-Head and Neck Surgery, Antwerp University Hospital, Antwerp, Belgium.
| Int J Lang Commun Disord. 2008 Sep 30:1-15.
DOI Direct Link |
Genetics: how the UKPDS contributed to determining the genetic landscape of Type 2 diabetes.
The identification and functional characterisation of genetic variants... | 9th September, 2008
| Diabetes Research Laboratories, Oxford Centre for Diabetes Endocrinology
| Diabet Med. 2008 Aug;25 Suppl 2:35-40.
DOI Direct Link |
Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.
CONTEXT: Insulin resistance, which associates with levels of... | 22nd August, 2008
| Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology,
| J Clin Endocrinol Metab. 2008 Jul;93(7):2859-65. Epub 2008 Apr 29.
DOI Direct Link |
Voltage-gated ion channels in human pancreatic beta-cells: electrophysiological characterization and role in insulin secretion.
OBJECTIVE: To characterize the voltage-gated ion channels in human... | 2nd August, 2008
| Oxford Centre for Diabetes Endocrinology and Metabolism, University of
| Diabetes. 2008 Jun;57(6):1618-28. Epub 2008 Apr 4.
DOI Direct Link |
Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon.
AIMS/HYPOTHESIS: Long-term exposure to NEFAs leads to inhibition of... | 16th July, 2008
| OCDEM, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.
| Diabetologia. 2008 Sep;51(9):1689-93. Epub 2008 Jul 12.
DOI Direct Link |
Genome-wide association studies for complex traits: consensus, uncertainty and challenges.
The past year has witnessed substantial advances in understanding the... | 14th May, 2008
| Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford,
| Nat Rev Genet. 2008 May;9(5):356-69.
DOI Direct Link |
Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome.
CONTEXT: Obesity-related predisposition to polycystic ovary syndrome... | 16th April, 2008
| Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology,
| J Clin Endocrinol Metab. 2008 Mar;93(3):999-1004. Epub 2007 Dec 18.
DOI Direct Link |
Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome.
OBJECTIVE: Abnormal ghrelin regulation may influence the development of... | 10th April, 2008
| Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill
| Eur J Endocrinol. 2008 Apr;158(4):511-6.
DOI Direct Link |
Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.
AIMS/HYPOTHESIS: Common variants of the gene encoding transcription factor... | 21st February, 2008
| Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill
| Diabetologia. 2007 Nov;50(11):2318-22. Epub 2007 Sep 6.
DOI Direct Link |
Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome.
OBJECTIVE: Application of the newly introduced Rotterdam criteria for... | 19th September, 2007
| Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill
| Clin Endocrinol (Oxf). 2007 Apr;66(4):513-7.
DOI Direct Link |
Metabolic syndrome in polycystic ovary syndrome.
Both metabolic syndrome (MS) and polycystic ovary syndrome (PCOS) are... | 31st August, 2007
| Diabetes Research Laboratories, Oxford Centre for Diabetes, Endocrinology
| Endokrynol Pol. 2007 Jan-Feb;58(1):34-41.
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[Bilharziasis or schistosomiasis]
Schistosomiasis has been known and described since Antiquity. However, the... | 30th June, 2007
| Service de parasitologie, CHRU hopital Bretonneau, 37044 Tours.
| Rev Prat. 2007 Jan 31;57(2):149-55.
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