Elbion AG

elbion discovers and develops new small molecule drugs. Inflammatory and central nervous system diseases with high unmet medical need and high commercial potential are at the center of elbion's project pipeline, which covers all stages from early "hits" to advanced clinical projects.

Contact Details: Meissner Str. 191 Radebeul D-01445 Germany Tel: 49.351.40430 Fax: 49.351.40433216 Email: press@elbion.com WWW: www.elbion.de/

Recent Publications by Elbion AG:
New GABA-modulating 1,2,4-oxadiazole derivatives and their anticonvulsant activity. A series of 3- and 5-aryl-1,2,4-oxadiazole derivatives were prepared and...	31st August, 2007	Department of Medicinal Chemistry, elbion AG, Meissner Strasse 191,	Eur J Med Chem. 2007 Jun;42(6):873-9. Epub 2007 Jan 12. DOI Direct Link
ELB139 an agonist at the benzodiazepine binding site increases 5-HT in the striatum and prefrontal cortex of rats: a microdialysis study. Benzodiazepines induce an immediate anxiolytic activity at the expense of...	23rd May, 2007	elbion AG, Pharmacology Department, Meissner Str. 191, 01445 Radebeul,	Pharmacol Biochem Behav. 2007 Jan;86(1):79-85. Epub 2006 Dec 22. DOI Direct Link
Synthesis, pharmacology, and structure-activity relationships of novel imidazolones and pyrrolones as modulators of GABAA receptors. New series of imidazolones and pyrrolones were synthesized. The compounds...	29th April, 2006	elbion AG, Meissner Strasse 191, D-01445 Radebeul, Germany, and Institute	J Med Chem. 2006 Mar 23;49(6):1855-66. DOI Direct Link
The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice. The selective phosphodiesterase 4 (PDE4) inhibitor AWD 12-281 is...	7th April, 2006	Department of Pharmacology, elbion AG, Meissner Str. 191, D-01445	J Pharm Pharmacol. 2005 Dec;57(12):1609-17. DOI Direct Link
Characterization in rats of the anxiolytic potential of ELB139 [1-(4-chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a new agonist at the benzodiazepine binding site of the GABAA receptor. Benzodiazepines are among the most effective drugs for the treatment of...	1st October, 2005	Department of Pharmacology, elbion AG, Meissner Strasse 191, D-01445	J Pharmacol Exp Ther. 2005 Aug;314(2):717-24. Epub 2005 Apr 28. DOI Direct Link
→View more Elbion AG research publications.

BioNews Results for Elbion AG:
Guidelines for cancer screening differ by group - AP	Guardian.co.uk:  Nov 23 2009 5:09AM Matching: ag
Annals of Internal Medicine Publishes New USPSTF Breast Cancer Screening Guidelines	Media Newswire:  Nov 22 2009 8:48PM Matching: ag
Medical News: Age Concern And Help The Aged Respond To Conservative Plans To Retain Vital Benefits For Older People, UK	BioFind:  Nov 22 2009 11:45AM Matching: ag
Age Concern And Help The Aged Respond To Conservative Plans To Retain Vital Benefits For Older People, UK	Medical News Today:  Nov 22 2009 11:40AM Matching: ag
Guidelines for cancer screening differ by group	KTRK TV:  Nov 22 2009 3:41AM Matching: ag
Promote your company here: BioNewsCast - Press Release Distribution	→View more Elbion AG news.

Elbion AG Clinical Trials:
ELB139 Given Orally to Patients With Concurrent Panic Disorder, Challenged by CO2 Inhalation After a Single Dose and One Week of Treatment

Elbion AG Patents:
US Patent No.	Title
7419987	7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
7309713	Use of the non-opiate analgesic drug flupirtine for the treatment of overactive bladder and associated diseases including urge incontinence, urinary flow problems as a result of prostate hyperplasia and irritable bowel syndrome
7211583	7-azaindoles and the use thereof as therapeutic agents
7169787	7-azaindoles, use thereof as phosphodiesterase 4 inhibitors and method for producing the same
7166637	Hydroxyindoles, their use as inhibitors of phosphodiesterase 4, and processes for preparing them
→View more Elbion AG patents.

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