EMD LEXIGEN

Founded in 1992 as a joint venture with Fuji Photo Film Ltd., EMD Lexigen Research Center Corp. (EMD Lexigen for short) was formed to screen Fuji’s chemical library for drug activities, with an initial focus on immune disorders and cancer.Our activities have evolved significantly since then. Having gained independence from Fuji Photo Film in 1997, EMD Lexigen has honed its activities to focus on developing proprietary immunocytokine and Fc-X fusion protein technologies for treatment of life-threatening diseases such as cancer and AIDS.

Contact Details: Bedford Campus45A Middlesex Turnpike Billerica Massachusetts 01821 United States of America Tel: 978 294 1100 Fax: 978 294 1101 Email: info@emdlexigen.com WWW: www.emdlexigen.com/

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Recent Publications by EMD LEXIGEN:
huBC1-IL12, an immunocytokine which targets EDB-containing oncofetal fibronectin in tumors and tumor vasculature, shows potent anti-tumor activity in human tumor models. IL-12 is a cytokine which showed anti-tumor effects in clinical trials,...	17th May, 2007	EMD Lexigen Research Center, 45A Middlesex Turnpike, Billerica, MA 01821,	Cancer Immunol Immunother. 2007 Apr;56(4):447-57. Epub 2006 Jul 28. DOI Direct Link
Engineering a pharmacologically superior form of leptin for the treatment of obesity. Leptin plays a central role in the homeostasis of body weight through its...	28th October, 2005	EMD-Lexigen Research Center, Bedford Campus, 45A Middlesex Turnpike,	Protein Eng Des Sel. 2005 Jan;18(1):1-10. DOI Direct Link
Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond. Erythropoietin (Epo) is a cytokine that controls the production of red...	4th October, 2005	EMD Lexigen Research Center Corp., 45A Middlesex Turnpike, Billerica, MA	Protein Eng Des Sel. 2005 Mar;18(3):111-8. Epub 2005 Apr 8. DOI Direct Link
An anti-CD20-IL-2 immunocytokine is highly efficacious in a SCID mouse model of established human B lymphoma. We have engineered an anti-CD20-interleukin 2 (IL-2) immunocytokine (ICK)...	9th June, 2005	EMD Lexigen Research Center, Bedford Campus, 45A Middlesex Tpk, Billerica,	Blood. 2005 May 15;105(10):3972-8. Epub 2005 Feb 3. DOI Direct Link
Immunocytokines: amplification of anti-cancer immunity. Many cancers elicit an anti-tumor immune response, which is nevertheless...	26th June, 2003	EMD Lexigen Research Center, Billerica, MA 01821, USA.	Cancer Immunol Immunother. 2003 May;52(5):297-308. Epub 2003 Jan 31. DOI Direct Link
→View more EMD LEXIGEN research publications.

BioNews Results for EMD LEXIGEN:
Mirna Therapeutics names Lammers CEO	Austin Business Journal:  Nov 13 2009 7:48PM Matching: emd
Digital Pharma: Byte-sized roundup	Pharmafocus:  Nov 13 2009 3:23PM Matching: emd
Digital Pharma: Byte-sized roundup	Pharmafocus:  Nov 13 2009 3:23PM Matching: emd
Merck Affiliate Tops Off Massachusetts Research Facility	CoStar Group:  Nov 12 2009 12:09AM Matching: emd
Mirna Therapeutics Appoints Dr. Paul Lammers as President and CEO	Yahoo! Canada:  Nov 12 2009 4:25PM Matching: emd
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EMD LEXIGEN Patents:
US Patent No.	Title
7365054	Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies
6838260	Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
6969517	Recombinant tumor specific antibody and use thereof
6992174	Reducing the immunogenicity of fusion proteins
7067110	Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
→View more EMD LEXIGEN patents.

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