Cambrex

Cambrex Corporation (NYSE:CBM) provides products and services to accelerate the development and commercialization of branded and generic small molecule therapeutics. Cambrex supports its customers worldwide with R&D and cGMP manufacturing facilities in the US and Europe, an excellent regulatory compliance record and strong expertise in various chemical technologies. Pharmaceutical Products & Services Cambrex has built a comprehensive platform of chemical technologies for the synthesis of small molecule active pharmaceutical ingredients (APIs). We have extensive experience developing drug substances from early stage through clinical development, up to launch and commercial supply – from grams to tons. Cambrex has a broad range of services, which include: route selection, process development, analytical development, process scale-up, safety assessments and optimization. Our core technologies and offerings include: Highly Potent & Cytotoxic Compounds, High Energy, Hydrogenation, Biocatalysis/Biotransformation, Chiral Synthesis, Controlled Substances, Nitration and Polymeric Drug Delivery, including Taste Masking. Generic APIs For generic drug companies, Cambrex supplies more than 70 APIs (including controlled substances) for pain management, cardiovascular, gastrointestinal, central nervous system, endocrine and respiratory indications. Cambrex manufactures these products using complex chemistry and technical expertise while maintaining its long-standing reputation of quality and reliability. We work with generic drug companies well in advance of drug patent expiration, provide a non-infringing process and file a Drug Master File (DMF) for the generic active pharmaceutical ingredients.

Contact Details: ONE MEADOWLANDS PLAZA, EAST RUTHERFORD New Jersey 07073 United States of America Tel: 201 804 3000 Fax: Email: pharma@cambrex.com WWW: www.cambrex.com/

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Recent Publications by Cambrex:
Kinetic characterization and in vitro toxicity evaluation of a luciferase less susceptible to HPV chemical inhibition. Enzyme-based in vitro toxicity assays are often susceptible to inhibition...	27th December, 2006	Cambrex North Brunswick, 661 Highway One, North Brunswick, NJ 08902, USA.	Toxicol In Vitro. 2006 Dec;20(8):1537-47. Epub 2006 Jul 12. DOI Direct Link
Differentiating primary human cells in rapid-throughput discovery applications. Primary cultures of human cells provide an increasingly important...	9th December, 2006	Cambrex Corporation, Baltimore, MD, USA.	Methods Mol Biol. 2007;356:121-8.
Creating a mutant luciferase resistant to HPV chemical inhibition by random mutagenesis and colony-level screening. Firefly luciferase covers a wide range of applications. One common usage...	31st August, 2006	Cambrex North Brunswick, North Brunswick, NJ 08902, USA.	Luminescence. 2006 May-Jun;21(3):135-42. DOI Direct Link

BioNews Results for Cambrex:
Fine chemical prospects brighten as focus shifts to technology and quality	ICIS:  Sep 29 2008 5:13PM Matching: cambrex
The Gut (Microbial translocation) is associated with sustained failure in CD4+ T-cell reconstitution in HIV-in	National AIDS Treatment Advocacy Project:  Sep 24 2008 7:36AM Matching: cambrex
High-potency unit opens at Phamatek	Outsourcing Pharma:  Sep 23 2008 8:14AM Matching: cambrex
High-potency unit opens at Phamatek	Outsourcing Pharma:  Sep 18 2008 5:19PM Matching: cambrex

Cambrex Patents:
US Patent No.	Title
7345191	Process for preparation of probucol derivatives
6586449	Nicotine-containing, controlled release composition and method
6828336	Nicotine-containing, controlled release composition and method
6849426	Methods and reagents for detecting endotoxin
6870065	Bifunctional boronic compound complexing reagents and complexes
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