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Galapagos

We are a genomics based drug discovery company, that has drug discovery programs based on proprietary disease modifying drug targets. Our vision is to bring novel drugs to the market in selected diseases areas for which there is a need for effective and safe medicines.
We focus on developing drugs that stop or reverse a disease state using novel targets that we identify through a patent protected genomics platform. To maximise the potential of the proprietary technology, we provide access to our target and drug discovery platform through our services division BioFocus DPI.Galapagos focuses its internal programs on developing new drugs in the bone and joint diseases- osteoarthritis, osteoporosis and rheumatoid arthritis. BioFocus DPI offers a full suite of target-to-drug discovery products and services to pharmaceutical and biotech companies, encompassing target discovery to validation and drug discovery services through to delivery of pre-clinical candidates. In addition, BioFocus DPI provides adenoviral reagents for rapid identification and validation of novel drug targets, natural and synthetic compound libraries for screening, and compound management facilities for compound delivery to multiple screening centers.


Contact Details:
BioFocus DPI9640 Towne Centre Drive
San Diego
California
92121
United States of America
Tel:1 858 455 8600
Fax:1 858 546 3081
Email:bd@glpg.com
WWW:

www.galapagosgenomics.com/




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Recent Publications by Galapagos:

Expression, purification and functional characterization of Wnt signaling co-receptors LRP5 and LRP6.
Activation of the Wnt signaling cascade plays a pivotal role during...
1st September, 2009
Protein Sciences, Galapagos, 102 route Gaston Roussel, F-93230 Protein Expr Purif. 2009 Aug 27.
DOI Direct Link
Wnt signaling and potential applications in bone diseases.
In the United States, it is estimated that $10-15 billion is spent...
17th October, 2008
Galapagos, 102 Gustave Roussel, 93230 Romainville, France. Curr Drug Targets. 2008 Jul;9(7):581-90.
Expression, purification and characterization of murine Dkk1 protein.
Dickkopf-1 (Dkk1) protein is a secreted inhibitor of canonical Wnt...
6th September, 2008
Galapagos SASU, Protein Sciences, 102 route de Noisy, 93230 Romainville, Protein Expr Purif. 2008 Jul;60(1):74-81. Epub 2008 Mar 31.
DOI Direct Link
Preventing establishment: an inventory of introduced plants in Puerto Villamil, Isabela Island, Galapagos.
As part of an island-wide project to identify and eradicate potentially...
17th July, 2008
Charles Darwin Research Station, Puerto Ayora, Galapagos, Ecuador. PLoS One. 2007 Oct 17;2(10):e1042.
DOI Direct Link
A convenient clinically relevant model of human breast cancer bone metastasis.
Breast cancer patients with advanced disease exhibit bone metastases,...
5th June, 2008
Galapagos SASU, 102 route de Noisy, Romainville, 93230, France. Clin Exp Metastasis. 2008;25(1):33-42. Epub 2007 Sep 28.
DOI Direct Link

View more Galapagos research publications.

Press Releases on Galapagos:

BioPortfolio Logo
realbuzz.com Top 25 Things to do Before You Die 9th September, 2009
LONDON, September 9 /PRNewswire/ -- Have you ever thought about what you want to do before you die? The 2007 film The Bucket List highlighted this with Jack Nicholson, and Morgan Freeman. With the
The Leona M. and Harry B. Helmsley Charitable Trust Donates $136 Million to Charities 21st April, 2009 The Leona M. and Harry B. Helmsley Charitable Trust
First Round of Grants to Aid Medical Research, Human Services, and Emergency Services NEW YORK, April 21 /PRNewswire/ -- The trustees of The Leona M. and Harry B. Helmsley Charitable Trust today
Celebrity Solstice to be Named in Sparkling Celebration 14th November, 2008 Celebrity Cruises
MIAMI, Nov. 14 /PRNewswire-FirstCall/ -- Celebrity Cruises today announced the Godmother of the most widely-heralded cruise ship to enter the market this year, Celebrity Solstice. Atypically, she
Click4Care Appoints Executive Leadership Team as Medical Management Product Takes Off 21st July, 2008 Click4Care
POWELL, Ohio, July 21 /PRNewswire/ -- Click4Care, a provider of pioneering medical management software, is building a leadership team to support its ever-expanding customer base in world class
Inpharmatica announces Chematica(TM) agreement with Novartis 1st May, 2004 Inpharmatica
Inpharmatica announces Chematica(TM) agreement with Novartis Novartis will use Inpharmatica's technology to identify protein targets for Novartis'

BioNews Results for Galapagos:

Galapagos Business Update
RBC Dain Rauscher:  Nov 13 2009 9:43AM Matching: galapagos
Galapagos third quarter 2009 financial results in line with management expectations
News-Medical.Net:  Nov 13 2009 12:32PM Matching: galapagos
Galapagos Business Update
Individual.com:  Nov 13 2009 7:11AM Matching: galapagos
Galapagos business update
Individual.com:  Nov 13 2009 7:11AM Matching: galapagos
Conference looks at commercialising bioscience from the sea
Cambridge Network:  Nov 12 2009 1:01AM Matching: galapagos
Promote your company here: BioNewsCast - Press Release Distribution

View more Galapagos news.

Galapagos Clinical Trials:

GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy Subjects

Galapagos Patents:

US Patent No.Title
7582640 Vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same
7501411 Triazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases
7485468 Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
7429459 Methods for identifying a compound that inhibits the procession of amyloid-beta protein production in a mammalian cell expressing APP and overexpressing a G-protein coupled receptor in the cell
7332337 Viral vectors having tissue tropism for T-lymphocytes, B- and mast cells

View more Galapagos patents.

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