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A.N..Belozersky Institute of Physico-Chemical Biology

The A.N.Belozersky Institute of Physico-Chemical Biology was founded in 1965 by Professor Andrey N. Belozersky, Vice-President of the USSR Academy of Sciences, Head of the Department of Plant Biochemistry of Moscow State University (MSU).Academician A.N.Belozersky, the first Director of the Institute, died on December 30, 1972. Since that time the position was occupied by Academician V.P.Skulachev. The scientific work of the Institute is directed by its Academic Council elected by researchers.Besides 16 research departments covering all major branches of modern physico-chemical biology, the Institute includes 5 service departments, where the most expensive equipment is localized.The total number of scientists and technicians is now about 220 and 100, respectively.
Among the most important findings published by researchers of the Institute, one can mention:
Direct measurement of generation of electric potential differences across intracellular membranes.
Discovery of H+- and Na+-motors, molecular mechanisms carrying out rotation of bacterial flagella.
Description of the Na+-cycle, a mechanism of membrane-linked energy transduction, alternative to the Mitchellian H+-cycle.
Discovery and elucidation of the function of a retina cell protein, recoverin.
Discovery of principles of photosynthetic apparatus organization, ensuring high efficiency for light energy conversion.
Topography and fine structure of the decoding center of the ribosome was established by means of originally developed chemical methods.
Creation of a new concept of intracellular transport of the plant virus genetic material.
Discovery of the structure and expression of several RNA virus genomes (hordei-potex- and closteroviruses).
Description of the tissue and age specificity of DNA methylation in animals and plants.


Contact Details:
Tel:
Fax:7 (095) 939-0338
Email:skulach@head.genebee.msu.su
WWW:

www.genebee.msu.su/




Recent Publications by A.N..Belozersky Institute of Physico-Chemical Biology:

Tritium planigraphy study of structural alterations in the coat protein of Potato virus X induced by binding of its triple gene block 1 protein to virions.
Alterations in Potato virus X (PVX) coat protein structure after binding...
29th October, 2009
A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State FEBS J. 2009 Oct 27.
DOI Direct Link
Investigation of the low-affinity oxidation site for exogenous electron donors in the Mn-depleted photosystem II complexes.
In the manganese-depleted photosystem II (PSII[-Mn]) preparations,...
23rd October, 2009
A.N.Belozersky Institute of Physico-Chemical Biology, Moscow State Biochim Biophys Acta. 2009 Dec;1787(12):1492-8. Epub 2009 Jul 17.
DOI Direct Link
Histidine 440 controls the opening of colicin E1 channels in a lipid-dependent manner.
The in vitro activity of many pore-forming toxins, in particular, the rate...
20th October, 2009
A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State Biochim Biophys Acta. 2009 Sep;1788(9):1962-6. Epub 2009 Jun 26.
DOI Direct Link
Myoglobin causes oxidative stress, increase of NO production and dysfunction of kidney's mitochondria.
Rhabdomyolysis or crush syndrome is a pathology caused by muscle injury...
7th October, 2009
A.N.Belozersky Institute of Physico-Chemical Biology, and Institute of Biochim Biophys Acta. 2009 Aug;1792(8):796-803. Epub 2009 Jun 21.
DOI Direct Link
Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation.
Mechanism-based inhibitors and both forward and reverse genetics have...
17th September, 2009
A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow Biochem J. 2009 Aug 27;422(3):405-21.
DOI Direct Link

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