BioPortfolio - Genomics Institute of the Novartis Research Foundation

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The Genomics Institute of the Novartis Research Foundation (GNF) has integrated state of the art technologies, making possible new approaches to complex biomedical problems in the neurosciences, immunology and cancer biology. These technologies cut across the life sciences and include genomics and proteomics tools, combinatorial chemistry, structural genomics and computational biology. The mission of the Institute is to exploit these technologies to identify new biological processes and understand the underlying mechanisms involved in human disease. These discoveries are being translated into human therapeutics by a preclinical drug discovery effort. GNF was founded in 1999 and currently houses over 400 employees. The location of the 260,000 square foot research center is in the heart of the Torrey Pines Science Park and surrounded by other centers of excellence such as the Scripps Research Institute (TSRI), Salk Institute and UCSD. This potentiates a wide range of interactions through meetings, seminars and collaborations.

Contact Details:
	10675 John Jay Hopkins Drive
	San Diego
	California
	92121
	United States of America
Tel:	858 812 1500
Fax:	858 812 1502
Email:	info@gnf.org
WWW:	www.gnf.org/

Recent Publications by Genomics Institute of the Novartis Research Foundation:
Parallel methods for expression and purification. Protein properties are highly diverse, making parallel expression and...	7th November, 2009	Genomics Institute of the Novartis Research Foundation, San Diego,	Methods Enzymol. 2009;463:767-85. DOI Direct Link
Cell-based optimization of novel benzamides as potential antimalarial leads. Screening our in-house compound collection using a cell based Plasmodium...	3rd November, 2009	Genomics Institute of the Novartis Research Foundation, 10675 John J.	Bioorg Med Chem Lett. 2009 Oct 28. DOI Direct Link
A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Two decades of research identified more than a dozen clock genes and...	29th October, 2009	Genomics Institute of the Novartis Research Foundation, San Diego, CA	Cell. 2009 Oct 2;139(1):199-210. Epub 2009 Sep 17. DOI Direct Link
Identification and Characterization of a Small Molecule Antagonist of Human VPAC2 Receptor. The neuropeptides vasoactive intestinal peptide (VIP) and pituitary...	27th October, 2009	Genomics Institute of the Novartis Research Foundation.	Mol Pharmacol. 2009 Oct 23. DOI Direct Link
Discovery of pyrimidine benzimidazoles as Src-family selective Lck inhibitors. Part II. A series of 4-amino-6-benzimidazole-pyrimidines was designed to target...	27th October, 2009	Genomics Institute of the Novartis Research Foundation (GNF), San Diego,	Bioorg Med Chem Lett. 2009 Dec 1;19(23):6691-5. Epub 2009 Oct 12. DOI Direct Link
→View more Genomics Institute of the Novartis Research Foundation research publications.

Press Releases on Genomics Institute of the Novartis Research Foundation:
Cell Therapeutics Targeting Potential Zevalin Label Expansion, Pixantrone and OPAXIO Drug Approvals to Grow Commercial Operations and Revenues in 2009	14th January, 2009	Cell Therapeutics, Inc.	SEATTLE, Jan. 14 /PRNewswire-FirstCall/ -- In meetings held in association with the JP Morgan Healthcare Conference in San Francisco, Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) reviewed
Cell Therapeutics Net Loss Declines as Operating Expenses Decrease By 58% in Third Quarter 2008	7th November, 2008	Cell Therapeutics, Inc.	SEATTLE, Nov. 7 /PRNewswire-FirstCall/ -- Cell Therapeutics, Inc. (CTI) (Nasdaq and MTA: CTIC) reported financial results for the quarter ended September 30, 2008. Total revenues for the quarter
GeneChip® CustomExpress™ 11-Micron Array Format Sets New Standard for	1st January, 1970	Affymetrics	GeneChip® CustomExpress™ 11-Micron Array Format Sets New Standard for Data Capacity: 61,000 Transcripts on a Single Array -- New Affymetrix GeneChip® CustomExpress™ array contains 1

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Genomics Institute of the Novartis Research Foundation

Recent Publications by Genomics Institute of the Novartis Research Foundation:

Press Releases on Genomics Institute of the Novartis Research Foundation: