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GTC BiotherapeuticsGTC Biotherapeutics develops, produces, and commercializes therapeutic proteins using transgenic animal technology. ATrynŽ, recombinant human antithrombin, is the first transgenically produced therapeutic protein approved anywhere in the world, having recently been approved by the European Commission (EMEA) for the prophylactic treatment of deep vein thrombosis in patients with hereditary antithrombin deficiency. ATrynŽ was approved for hereditary antithrombin deficiency in the United States (FDA) in February 2009, and remains the only recombinant form of the molecule available for clinical use. ATrynŽ is produced in the milk of goats using micro-injection technology to incorporate a human antithrombin transgene. In addition to ATrynŽ, GTC is developing additional recombinant proteins and monoclonal antibodies. These products have potential applications in hematology, oncology, and autoimmune diseases. GTC has active development and commercialization relationships with Lundbeck Inc. and LFB Paris.
| Contact Details: |
| 175 Crossing Blvd. |
| Framingham |
| Massachusetts |
| 01702 |
| United States of America |
| Tel: | (508) 620-9700 |
| Fax: | (508) 370-3797 |
| Email: | |
| WWW: | www.gtc-bio.com/
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Recent Publications by GTC Biotherapeutics: |  |
Production of recombinant albumin by a herd of cloned transgenic cattle.
Purified plasma derived human albumin has been available as a therapeutic... | 26th September, 2009
| GTC Biotherapeutics, Inc., Framingham, MA 01701-9322, USA.
| Transgenic Res. 2009 Jun;18(3):361-76. Epub 2008 Nov 22.
DOI Direct Link |
Repeat superovulation, non-surgical embryo recovery, and surgical embryo transfer in transgenic dairy goats.
We investigated the capability of repeat superovulation and non-surgical... | 12th March, 2008
| GTC Biotherapeutics,
| Theriogenology. 2008 Jan 15;69(2):197-203. Epub 2007 Oct 29.
DOI Direct Link |
Characterization of calcium oscillation patterns in caprine oocytes induced by IVF or an activation technique used in nuclear transfer.
Routine activation of nuclear transfer (NT) eggs involves the application... | 13th July, 2006
| GTC Biotherapeutics Inc., 175 Crossing Boulevard, Framingham, MA 01702,
| Theriogenology. 2006 May;65(8):1575-86. Epub 2005 Oct 21.
DOI Direct Link |
Synchronization of goat fibroblast cells at quiescent stage and determination of their transition from G0 to G1 by detection of cyclin D1 mRNA.
A number of studies have reported that donor cells consisting of serum... | 16th November, 2005
| GTC-Biotherapeutics Inc., Framingham, Massachusetts 01701, USA.
| Cloning Stem Cells. 2004;6(2):58-66.
DOI Direct Link |
Health and reproductive profiles of malaria antigen-producing transgenic goats derived by somatic cell nuclear transfer.
Nuclear transfer (NT) using transfected primary cells is an efficient... | 5th October, 2005
| GTC Biotherapeutics, Inc., Framingham, Massachusetts 01701, USA.
| Cloning Stem Cells. 2005;7(2):107-18.
DOI Direct Link |
→View more GTC Biotherapeutics research publications. |
Press Releases on GTC Biotherapeutics:
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| NORD to Honor Rare Disease Pioneers |
11th May, 2009 |
National Organization for Rare Disorders (NORD) |
DANBURY, Conn., May 11 /PRNewswire-USNewswire/ -- The National Organization for Rare Disorders (NORD) will honor a senior U.S. Senator, a top Administration official, a cutting-edge television
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| Genzyme Reports Strong Second-Quarter Growth |
23rd July, 2008 |
Genzyme Corporation |
CAMBRIDGE, Mass., July 23 /PRNewswire-FirstCall/ -- Genzyme Corporation
(Nasdaq: GENZ) today reported strong sales and profit growth in the second
quarter, along with significant progress in its
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| The Scientific Business of Thomson Reuters Publishes Pharma Matters - a Series of Reviews Covering Various Aspects of the Pharmaceutical Pipeline |
4th June, 2008 |
The Scientific business of Thomson Reuters |
LONDON and PHILADELPHIA, June 4 /PRNewswire/ -- Thomson Reuters, the
world's leading source of intelligent information for businesses and
professionals, has announced the availability of the
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