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The Hope Heart InstituteThe Hope Heart Institute was founded in 1959 by Lester R. Sauvage, MD, a world-renowned cardiovascular surgeon and research scientists. Dr. Sauvage and The Hope earned international recognition in 1962 through pioneering coronary artery bypass graft (CABG) surgery. Today, The Hope's research remains at the forefront of the cardiovascular field—and our health education publications reach nearly 5 million readers a year.
| Contact Details: |
| 1710 E Jefferson Street |
| Seattle |
| Washington |
| 98122 |
| United States of America |
| Tel: | 206-903-2001 |
| Fax: | 206-903-2144 |
| Email: | info@hopeheart.org |
| WWW: | www.hopeheart.org/

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Recent Publications by The Hope Heart Institute: |  |
Purification of SPARC/osteonectin.
SPARC is a matricellular protein that regulates cell adhesion,... | 1st March, 2008
| The Hope Heart Institute, Seattle, Washington, USA.
| Curr Protoc Cell Biol. 2003 Feb;Chapter 10:Unit 10.11.
DOI Direct Link |
Vascular graft healing. III. FTIR analysis of ePTFE graft samples from implanted bigrafts.
A bigraft, composed of a 30-microm internodal distance expanded... | 13th December, 2005
| Department of Polymer Chemistry, The Hope Heart Institute, Seattle,
| J Biomed Mater Res B Appl Biomater. 2004 Aug 15;70(2):223-32.
DOI Direct Link |
The regulated synthesis of versican, decorin, and biglycan: extracellular matrix proteoglycans that influence cellular phenotype.
The principal extracellular matrix (ECM) chondroitin/dermatan sulfate... | 5th May, 2005
| Department of Vascular Biology, The Hope Heart Institute, Seattle, WA
| Crit Rev Eukaryot Gene Expr. 2004;14(3):203-34.
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SPARC regulates TGF-beta1-dependent signaling in primary glomerular mesangial cells.
Secreted protein acidic and rich in cysteine (SPARC), a member of the... | 8th March, 2005
| Department of Vascular Biology, The Hope Heart Institute, Seattle,
| J Cell Biochem. 2004 Apr 1;91(5):915-25.
DOI Direct Link |
SPARC and tumor growth: where the seed meets the soil?
Matricellular proteins mediate interactions between cells and their... | 3rd February, 2005
| Department of Vascular Biology, The Hope Heart Institute, 1124 Columbia
| J Cell Biochem. 2004 Jul 1;92(4):679-90.
DOI Direct Link |
→View more The Hope Heart Institute research publications. |
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