Institute for Diabetes Discovery

The Institute for Diabetes Discovery, LLC, (IDD) is the largest privately-held biopharmaceutical company in the United States dedicated to the research and discovery of novel drugs and therapeutics for diabetes. Founded in 1995 in Branford, Connecticut, IDD is the flagship institute under the umbrella of the Institutes for Pharmaceutical Discovery, LLC. The magnitude of the worldwide health and economic problems created by diabetes is staggering. The incidence of diabetes is reaching epidemic proportions and is the fourth leading cause of death in developed countries. In the United States, 18.2 million Americans suffer from this devastating disease, 1.3 million new cases will be diagnosed each year, and total healthcare treatment costs exceed $132 billion annually. Diabetes is a disease that affects virtually every tissue of the body with long term and severe damage. It spares no group - attacking men, women, children, the elderly and people from every racial background

Contact Details: 23 Business Park Drive Branford Connecticut 06405 United States of America Tel: (203) 315-4000 Fax: Email: info@idd-diabetes.com WWW: www.idd-discovery.com/

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Recent Publications by Institute for Diabetes Discovery:
The use of a high-throughput luminescent method to assess CYP3A enzyme induction in cultured rat hepatocytes. Assessment of a new chemical entity for cytochrome P450 (CYP) enzyme...	27th September, 2008	Institute for Diabetes Discovery, 23 Business Park Drive, Branford, CT	In Vitro Cell Dev Biol Anim. 2008 May-Jun;44(5-6):129-34. Epub 2008 Apr DOI Direct Link
Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74. Niacin is known to exert profound beneficial effects on cholesterol levels...	18th March, 2006	The Institute for Diabetes Discovery, 23 Business Park Drive, Branford, CT	Biochem Biophys Res Commun. 2006 Feb 10;340(2):482-90. Epub 2005 Dec 19. DOI Direct Link
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. Recent efforts to identify treatments for chronic diabetic complications...	4th June, 2005	The Institute for Diabetes Discovery, LLC, 23 Business Park Drive,	J Med Chem. 2005 May 5;48(9):3141-52. DOI Direct Link
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications. Recent efforts to identify treatments for chronic diabetic complications...	19th March, 2005	The Institute for Diabetes Discovery, LLC, 23 Business Park Drive,	Bioorg Med Chem. 2004 Nov 1;12(21):5661-75. DOI Direct Link
Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1. In addition to having a major role in energy homeostasis, leptin is...	4th December, 2002	Department of Molecular Biology, Institute for Diabetes Discovery, 25	J Biol Chem. 2002 Sep 13;277(37):34601-9. Epub 2002 Jun 25. DOI Direct Link
→View more Institute for Diabetes Discovery research publications.

BioNews Results for Institute for Diabetes Discovery:
NIH Funding For New Epigenomics Initiative	Medical News Today:  Oct 5 2008 8:07AM Matching: institute diabetes discovery
Fraternal Order of Eagles Pledges to Raise $25 Million for UI Diabetes Research	Newswise:  Sep 17 2008 6:16AM Matching: institute diabetes discovery
Fraternal Order of Eagles pledges to raise $25 million for UI diabetes research	Genetic Engineering News:  Sep 17 2008 1:01AM Matching: institute diabetes discovery
Receptor activation protects retina from diabetes destruction	Genetic Engineering News:  Sep 9 2008 4:14PM Matching: institute diabetes discovery
NIH tackles urologic chronic pelvic pain disorders	News-Medical.Net:  Sep 8 2008 1:40AM Matching: institute diabetes discovery
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