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Institute for Diabetes DiscoveryThe Institute for Diabetes Discovery, LLC, (IDD) is the largest privately-held biopharmaceutical company in the United States dedicated to the research and discovery of novel drugs and therapeutics for diabetes. Founded in 1995 in Branford, Connecticut, IDD is the flagship institute under the umbrella of the Institutes for Pharmaceutical Discovery, LLC. The magnitude of the worldwide health and economic problems created by diabetes is staggering. The incidence of diabetes is reaching epidemic proportions and is the fourth leading cause of death in developed countries. In the United States, 18.2 million Americans suffer from this devastating disease, 1.3 million new cases will be diagnosed each year, and total healthcare treatment costs exceed $132 billion annually. Diabetes is a disease that affects virtually every tissue of the body with long term and severe damage. It spares no group - attacking men, women, children, the elderly and people from every racial background
| Contact Details: |
| 23 Business Park Drive |
| Branford |
| Connecticut |
| 06405 |
| United States of America |
| Tel: | (203) 315-4000 |
| Fax: | |
| Email: | info@idd-diabetes.com |
| WWW: | www.idd-discovery.com/

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Recent Publications by Institute for Diabetes Discovery: |  |
Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]ac etic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
Efforts to identify treatments for chronic diabetic complications have... | 16th June, 2009
| The Institute for Diabetes Discovery, LLC, 23 Business Park Drive,
| Bioorg Med Chem Lett. 2009 Apr 1;19(7):2006-8. Epub 2009 Feb 12.
DOI Direct Link |
The use of a high-throughput luminescent method to assess CYP3A enzyme induction in cultured rat hepatocytes.
Assessment of a new chemical entity for cytochrome P450 (CYP) enzyme... | 27th September, 2008
| Institute for Diabetes Discovery, 23 Business Park Drive, Branford, CT
| In Vitro Cell Dev Biol Anim. 2008 May-Jun;44(5-6):129-34. Epub 2008 Apr
DOI Direct Link |
Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
Niacin is known to exert profound beneficial effects on cholesterol levels... | 18th March, 2006
| The Institute for Diabetes Discovery, 23 Business Park Drive, Branford, CT
| Biochem Biophys Res Commun. 2006 Feb 10;340(2):482-90. Epub 2005 Dec 19.
DOI Direct Link |
Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.
Recent efforts to identify treatments for chronic diabetic complications... | 4th June, 2005
| The Institute for Diabetes Discovery, LLC, 23 Business Park Drive,
| J Med Chem. 2005 May 5;48(9):3141-52.
DOI Direct Link |
Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications.
Recent efforts to identify treatments for chronic diabetic complications... | 19th March, 2005
| The Institute for Diabetes Discovery, LLC, 23 Business Park Drive,
| Bioorg Med Chem. 2004 Nov 1;12(21):5661-75.
DOI Direct Link |
→View more Institute for Diabetes Discovery research publications. |
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