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The Immune Response Corporation

The Immune Response Corporation (OTCBB: IMNR.OB) is an immuno-pharmaceutical company focused on developing products to treat autoimmune and infectious diseases. The Company’s lead immune-based therapeutic product candidates are NeuroVax™ for the treatment of MS and IR103 for the treatment of HIV infection. Both of these therapies are in Phase II clinical development and are designed to stimulate pathogen-specific immune responses aimed at slowing or halting the rate of disease progression.
NeuroVax™, which is based on the Company’s patented T-cell receptor (TCR) peptide technology, has shown potential clinical value in the treatment of relapsing forms of MS. NeuroVax™ has been shown to stimulate strong, disease-specific cell-mediated immunity in nearly all patients treated and appears to work by enhancing levels of FOXP3+ Treg cells that are able to down-regulate the activity of pathogenic T-cells that cause MS. Increasing scientific findings have associated diminished levels of FOXP3+ Treg cell responses with the pathogenesis and progression of MS and other autoimmune diseases such as rheumatoid arthritis (RA), psoriasis and Crohn’s disease. In addition to MS, the Company has open Investigational New Drug Applications (IND) with the FDA for clinical evaluation of TCR peptide-based immune-based therapies for RA and psoriasis


Contact Details:
5931 Darwin Court
Carlsbad
California
92008
United States of America
Tel:760-431-7080
Fax:760-431-8636
Email:
WWW:

www.imnr.com/




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Recent Publications by The Immune Response Corporation:

Identification of reciprocally regulated gene modules in regenerating dorsal root ganglion neurons and activated peripheral or central nervous system glia.
Differential gene expression in the rat after injury of dorsal root...
3rd December, 2003
The Immune Response Corporation, 5935 Darwin Court, Carlsbad, California J Cell Biochem. 2003 Apr 1;88(5):970-85.
DOI Direct Link
HIV-specific immunity during structured antiviral drug treatment interruption.
The immunologic correlates associated with control of viremia in HIV...
1st November, 2003
The Immune Response Corporation, 5935 Darwin Court, Carlsbad, CA 92008, Vaccine. 2003 Mar 7;21(11-12):1066-71.
Propofol phosphate, a water-soluble propofol prodrug: in vivo evaluation.
After a single IV injection of the water-soluble propofol prodrug propofol...
26th November, 2002
Chemistry Department, The Immune Response Corporation, 5935 Darwin Court, Anesth Analg. 2002 Nov;95(5):1285-92, table of contents.
Novel membrane-bound GM-CSF vaccines for the treatment of cancer: generation and evaluation of mbGM-CSF mouse B16F10 melanoma cell vaccine.
Cancer vaccines composed of tumor cells engineered to secrete...
18th October, 2002
Division of Cancer, The Immune Response Corporation, 5935 Darwin Court, Gene Ther. 2002 Oct;9(19):1302-11.
DOI Direct Link
Maternal and newborn immunization with a human immunodeficiency virus-1 immunogen in a rodent model.
We examined immunization with an inactivated, gp120-depleted human...
3rd October, 2002
The Immune Response Corporation, Carlsbad, California 92008, USA. Immunology. 2002 Aug;106(4):549-53.

View more The Immune Response Corporation research publications.

Press Releases on The Immune Response Corporation:

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New Report from PharmaPlus: HIV Pipelines & Deals 1st December, 2003 Pharmaplus
New Report from PharmaPlus: HIV Pipelines & Deals  At the end of November 2003 the joint United Nations Program on HIV/AIDS and the World Health Organization presented
The Infectious Diseases Review brings you the latest news, expert 1st January, 1970 Datamonitor
Datamonitor's October edition of the Infectious Diseases Review brings you the latest news, expert analysis and research in the infectious

BioNews Results for The Immune Response Corporation:

Medical News: Novartis Influenza A(H1N1) 2009 Vaccine US Interim Data Show Lower Doses Of Antigen May Suffice To Generate A Protective Immune Response
BioFind:  Nov 22 2009 12:37PM Matching: immune response
An Overactive Immune Response Responsible for Viral Infections Among Elderly
MedIndia:  Nov 21 2009 5:09AM Matching: immune response
An Overactive Immune Response Linked To Viral Infections Among Elderly
Medical News Today:  Nov 19 2009 7:29PM Matching: immune response
Medical News: An Overactive Immune Response Linked To Viral Infections Among Elderly
BioFind:  Nov 19 2009 5:38PM Matching: immune response
New Culprit for Viral Infections Among ElderlyEURAn Overactive Immune Response
Yale University:  Nov 18 2009 6:19AM Matching: immune response
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View more The Immune Response Corporation news.

The Immune Response Corporation Patents:

US Patent No.Title
6737066 HIV immunogenic compositions and methods
5985552 Vaccination and methods against diseases resulting from pathogenic responses by specific T cell populations
5916806 Prevention and treatment of retroviral disease
5895650 Prevention and treatment of retroviral disease
5891432 Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same

View more The Immune Response Corporation patents.

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