Karo Bio AB

Karo Bio is an innovative drug discovery and development company specializing in nuclear receptors for the development of novel pharmaceuticals. The company has a strong project portfolio primarily targeting metabolic diseases such as diabetes, obesity, atherosclerosis and dyslipidemia. Karo Bio has expanded from being a drug discovery company by adding in-house preclinical development resources and expertise for clinical development. The company also has two strategic collaborations with international pharmaceutical companies for developing innovative therapies for the treatment of common diseases. Karo Bio has been listed on the Stockholm stock exchange since 1998

Contact Details: Novum Huddinge S-141 57 Sweden Tel: 46 8 608 6000 Fax: 46 8 774 8261 Email: science@karobio.se WWW: www.karobio.se/

Recent Publications by Karo Bio AB:
Underlying mechanisms mediating the antidepressant effects of estrogens. BACKGROUND: There is an increased risk for depressive symptoms and...	11th November, 2009	Karo Bio AB, Novum SE-141 57, Huddinge, Sweden.	Biochim Biophys Acta. 2009 Nov 10. DOI Direct Link
ERbeta a Novel Estrogen Receptor Offers the Potential for New Drug Development. There is increasing interest in developing better drugs for improving the...	15th April, 2008	Karo Bio AB, Huddinge, Sweden.	Trends Endocrinol Metab. 1998 Dec;9(10):387-95.
The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans. Atherosclerotic cardiovascular disease is a major problem despite the...	7th February, 2008	Karo Bio AB, Novum Research Park, S-141 57 Huddinge, Sweden.	Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):663-7. Epub 2007 Dec 26. DOI Direct Link
Thyroid receptor ligands. Part 8: Thyromimetics derived from N-acylated-alpha-amino acid derivatives displaying modulated pharmacological selectivity compared with KB-141. Based on the scaffold of the pharmacologically selective thyromimetic 2b,...	2nd October, 2007	Karo Bio AB, Novum, Huddinge S-141 57, Sweden.	Bioorg Med Chem Lett. 2007 Aug 1;17(15):4131-4. Epub 2007 May 21. DOI Direct Link
Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity. Based on the concept of 'indirect antagonism' of nuclear receptors, a...	26th July, 2007	Karo Bio AB,	Bioorg Med Chem Lett. 2007 Apr 1;17(7):2018-21. Epub 2007 Jan 13. DOI Direct Link
→View more Karo Bio AB research publications.

BioNews Results for Karo Bio AB:
Prospectus For Karo Bio??s Rights Issue Now Available	Therapeutics Daily:  Nov 11 2009 11:11AM Matching: karo bio ab
Pressrelease From The Extraordinary General Meeting Of Karo Bio Ab (publ)	Therapeutics Daily:  Nov 11 2009 10:17AM Matching: karo bio ab
Prospectus for Karo Bio AB's Rights Issue Now Available	BioSpace:  Nov 11 2009 7:44PM Matching: karo bio ab
Karo Bio??s Nominating Committee For The Annual General Meeting 2010 Appointed	Therapeutics Daily:  Nov 10 2009 11:18AM Matching: karo bio ab
Karo Bio's Nominating Committee For The Annual General Meeting 2010 Appointed	Pharma Live:  Nov 10 2009 5:03PM Matching: karo bio ab
Promote your company here: BioNewsCast - Press Release Distribution	→View more Karo Bio AB news.

Karo Bio AB Patents:
US Patent No.	Title
7521439	Glucocorticoid receptor ligands for the treatment of metabolic disorders
6617114	Identification of drug complementary combinatorial libraries
6525188	Nuclear retinoic acid co-receptor
6492424	Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders
6468975	Liver specific bile acid derivatives of the glucocorticoid antagonist RU486
→View more Karo Bio AB patents.

Contact BioPortfolio for a quote for a customised Excel verision of BioCorporate or BioEmail databases.

This page has been viewed 213 times since April 2007, the link to the organisation's website has been followed 32 times

Search for more companies in Novum

Search for more companies in Huddinge

This site uses Thumbshots previews, resources from the NCBI applied. Maps are centred on zip/postcodes and should not be relied upon for exact building locations. Some information on this page has been collected automatically and may not have been verified.
BioPortfolio search results for Karo Bio AB