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KineMedKineMed was founded in 1999 to provide kinetic solutions to fundamental problems in disease management and drug development. Although it is widely recognized that all biological systems are characterized by flux (polymers are synthesized and degraded; metabolite traverse pathways to provide energy; cells die and are replaced), virtually no tests in biomedicine in the year 2004 measure dynamic fluxes of molecules. A void therefore exists in the contemporary drug development/diagnostic repertoire, analogous to the state of photography before the development of moving pictures. KineMed's tests, termed KineMarkers™, fill this void by measuring molecular kinetics in living systems, including humans.
| Contact Details: |
| 5980 Horton StreetSuite 400 |
| Emeryville |
| California |
| 94608 |
| United States of America |
| Tel: | 510.655.6525 |
| Fax: | 510.655.6506 |
| Email: | info@kinemed.com |
| WWW: | www.kinemed.com/
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Recent Publications by KineMed: |  |
A stable isotope method for the simultaneous measurement of matrix synthesis and cell proliferation in articular cartilage in vivo.
OBJECTIVE: Measurements of cell proliferation and matrix synthesis in... | 5th November, 2009
| KineMed,
| Osteoarthritis Cartilage. 2009 Jul;17(7):923-32. Epub 2009 Feb 7.
DOI Direct Link |
Isolation of malignant B cells from patients with chronic lymphocytic leukemia (CLL) for analysis of cell proliferation: Validation of a simplified method suitable for multi-center clinical studies.
BACKGROUND: Heavy water ((2)H(2)O) labelling of DNA enables the... | 27th October, 2009
| KineMed, Inc., 5980 Horton Street, Emeryville, CA 94608, USA.
| Leuk Res. 2009 Oct 23.
DOI Direct Link |
A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes.
Treatment of type 2 diabetes mellitus (T2DM) patients with pioglitazone... | 10th February, 2009
| KineMed, Inc. Emeryville, CA, USA.
| J Lipid Res. 2008 Dec;49(12):2657-63. Epub 2008 Jul 18.
DOI Direct Link |
Heavy water labeling of DNA for measurement of cell proliferation and recruitment during primary murine lymph node responses against model antigens.
Lymph node (LN) responses to antigens involve inflammatory lymphocyte... | 16th September, 2008
| KineMed Inc., 5980 Horton Street, Emeryville, CA 94608, USA.
| J Immunol Methods. 2008 Aug 20;337(1):24-34. Epub 2008 Jun 13.
DOI Direct Link |
Measurement of very low rates of cell proliferation by heavy water labeling of DNA and gas chromatography/pyrolysis/isotope ratio-mass spectrometric analysis.
DNA replication during S-phase represents a biochemical metric of cell... | 20th February, 2008
| KineMed Inc., 5980 Horton Street, Emeryville, California 94608, USA.
| Nat Protoc. 2007;2(12):3058-62.
DOI Direct Link |
→View more KineMed research publications. |
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