Molecular Templates Inc.

Molecular Templates Inc. is creating an entirely new generation of potent anti-cancer agents based on proprietary applied proteomics technologies.The novel therapeutic agents in development by MTI are aimed particularly at melanoma, prostate and other metastatic cancers. Such agents are derived from the sophisticated mutation and selection of Shiga-like toxin (SLT) variants using recombinant DNA and proprietary ‘applied proteomics’ technologies.
New SLT therapeutic agents are created via a systematic approach involving the generation of a large number of mutant SLT genetic sequences that form a permanent combinatorial DNA library. From the library, SLT mutant genes are expressed and the corresponding protein toxins are screened for their ability to kill cancer cell-lines, whilst leaving normal human cell-lines unharmed.

Contact Details: MaRS Centre, 101 College Street, Suite 150 Toronto Ontario M5H 3W4 Canada Tel: 416 946 2875 Fax: 416 946 6529 Email: randal@moleculartemplates.com WWW: www.moleculartemplates.com/

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