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NiKem Research s.r.l.

Today NiKem is an integrated drug discovery company. Although the company started as a service provider, over their first few years NiKem invested heavily in people and equipment, and succeeded in building a robust capability in drug discovery. Now, with all the necessary biology functions and a powerful chemitechnology platform, NiKem’s scientists have all the tools necessary to bridge the gap between biology discovery and preclinical development.


Contact Details:
Via Zambeletti, 25
Baranzate
Milano
20021
Italy
Tel:39 02 356941
Fax:39 02 356947606
Email:info@nikemresearch.com
WWW:

www.nikemresearch.com/




Recent Publications by NiKem Research s.r.l.:

Evaluation of in vitro brain penetration: optimized PAMPA and MDCKII-MDR1 assay comparison.
Parallel artificial membrane permeability assay (PAMPA) is arising in...
25th January, 2008
Analytical and Developability Department, NiKem Research S.r.l., Via Int J Pharm. 2007 Dec 10;345(1-2):125-33. Epub 2007 May 31.
DOI Direct Link
New perspectives in bio-analytical techniques for preclinical characterization of a drug candidate: UPLC-MS/MS in in vitro metabolism and pharmacokinetic studies.
Lead optimization requires rapid bio-analytical turnover for the...
4th October, 2007
NiKem Research S.r.l., V. Zambeletti 25, 20021 Baranzate, Milano, Italy. J Pharm Biomed Anal. 2007 Jul 27;44(3):665-73. Epub 2006 Dec 17.
DOI Direct Link
Cell penetrable peptoid carrier vehicles: synthesis and evaluation.
Using a highly efficient solid-phase route a series of fluorescein...
11th February, 2004
NiKem Research S.r.l., Via Zambelletti, 25, 20021 Baranzate di Bollate Chem Commun (Camb). 2003 Sep 21;(18):2312-3.
Selective inhibition of osteoclast vacuolar H(+)-ATPase.
The proton pump expressed on the plasma membrane of bone resorbing...
4th March, 2003
NiKem Research S.r.l., Via Zambeletti 25, 20021 Baranzate di Bollate, Curr Pharm Des. 2002;8(23):2033-48.

NiKem Research s.r.l. Patents:

US Patent No.Title
7220769 Azolylbenzamides and analogues and their use for treating osteoporosis
6903117 Indole derivatives for the treatment of osteoporosis
6787550 Indole derivatives and their use for the treatment of osteoporosis amongst other applications

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