NimbleGen Systems Inc.

NimbleGen Systems, the leading supplier of flexible high-density microarray products and services, is enabling a new era of "High-Definition GenomicsSM." NimbleGen uniquely produces high-density arrays of isothermal long oligos that provide superior results for advanced genomic analysis methods such as CGH, ChIP, microbial whole-genome resequencing and expression tiling. NimbleGen's High-Definition Genomics enables scientists to obtain and integrate complex genetic data sets not previously accessible, providing a much clearer understanding of genomics and systems biology. This improved performance is made possible by NimbleGen's Maskless Array Synthesis (MAS) technology, which uses digital light processing and rapid, high-yield photochemistry to synthesize DNA.

Contact Details: 1 Science Court Madison Wisconsin 53711 United States of America Tel: (608) 218-7600 Fax: (608) 218-7601 Email: WWW: www.nimblegen.com/

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Recent Publications by NimbleGen Systems Inc.:
Direct selection of human genomic loci by microarray hybridization. We applied high-density microarrays to the enrichment of specific...	16th January, 2008	NimbleGen Systems Inc., 1 Science Court, Madison, Wisconsin 53711, USA.	Nat Methods. 2007 Nov;4(11):903-5. Epub 2007 Oct 14. DOI Direct Link
Methods in high-resolution, array-based comparative genomic hybridization. A method of high resolution, array-based comparative genomic hybridization...	13th December, 2007	NimbleGen Systems Inc., Madison, WI, USA.	Methods Mol Biol. 2007;381:189-211.
Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori. We developed a microarray hybridization-based method, 'comparative genome...	18th January, 2006	NimbleGen Systems Inc., One Science Court, Madison, Wisconsin 53711, USA.	Nat Methods. 2005 Dec;2(12):951-3. Epub 2005 Nov 18. DOI Direct Link
Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH. Understanding the genes and genetic pathways targeted by recurrent...	13th December, 2005	NimbleGen Systems Inc., Madison, WI 53711, USA.	Genes Chromosomes Cancer. 2005 Nov;44(3):305-19. DOI Direct Link
Light-directed 5'-->3' synthesis of complex oligonucleotide microarrays. Light-directed synthesis of high-density microarrays is currently...	17th April, 2003	NimbleGen Systems Inc., One Science Court, Madison, WI 53711, USA.	Nucleic Acids Res. 2003 Apr 1;31(7):e35.
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Press Releases on NimbleGen Systems Inc.:
Exclusive Cooperation Between RZPD and NimbleGen Systems Enables Faster	1st January, 1970	Rzpd	Exclusive Cooperation Between RZPD and NimbleGen Systems Enables Faster and More Flexible Microarray Analyses Berlin (December 10, 2004) - RZPD Deutsches Ressourcenzentrum für Genomforschung

NimbleGen Systems Inc. Patents:
US Patent No.	Title
7422851	Correction for illumination non-uniformity during the synthesis of arrays of oligomers
7157229	Prepatterned substrate for optical synthesis of DNA probes
7037659	Apparatus for constructing DNA probes having a prismatic and kaleidoscopic light homogenizer

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