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NMT Medical
Download detailed PDF Members: NMT Medical – Bringing closure to cardiac sources of stroke NMT Medical, Inc. is a publicly traded company (Nasdaq symbol NMTI), based in Boston, Massachusetts, that designs, develops, and markets innovative medical devices for the minimally invasive (non-surgical) treatment of patients who have cardiac sources of embolic stroke. Worldwide, approximately 500,000 people every year suffer an embolic stroke due to a condition called patent foramen ovale (PFO). It is estimated that PFO occurs in approximately 25% of the population. NMT’s PFO closure products are designed to treat patients who have experienced PFO-induced stroke and live in fear of another. The traditional therapy for embolic stroke is lifelong anticoagulation drug regimens. These regimens impose significant lifestyle restrictions on patients, often have side effects and rely heavily on individual patient compliance - which is not practical or achievable in all cases. Should the regimen not be effective, a further stroke could occur at any time. The societal costs of stroke disability are well documented - the personal costs immeasurable. With NMT’s products, non-surgical, catheter-based closure of the PFO can usually be achieved in less than an hour. This therapy offers peace of mind for the patient and lasts a lifetime. NMT recently embarked on a 1600 patient randomized, controlled clinical trial, called CLOSURE I, designed to evaluate the effectiveness of transcatheter PFO closure using the company's proprietary STARFlex® cardiac septal repair implant compared to best medical therapy. NMT Medical was the first company to gain regulatory approvals in the United States and Europe for devices to be used for the non-surgical closure of the PFO. Our leadership in PFO closure is further demonstrated by the length of our experience and the number of implants in this application. More than 20,000 PFO procedures have been performed worldwide.
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