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Chromos Molecular Systems IncorporatedChromos Molecular Systems Inc. (“CHROMOS”; TSE: CHR) is a public Canadian biotechnology company leading the development of innovative therapies using a proprietary gene delivery and expression system for the production of therapeutic proteins and cell-mediated gene therapies to treat disease.
Chromos is achieving this objective with a unique mammalian chromosome technology platform from which multiple product candidates can be developed. Chromos' technology, referred to as The ACE System, is a unique and powerful vehicle for carrying genes into cells. It offers competitive advantages over current systems in that it permits the rapid and efficient insertion of selected genes, allows for the long term and stable expression of large, single or multiple proteins, and provides a means to selectively and predictably control protein expression. Furthermore, this technology has an extremely large DNA carrying capacity, allowing the placement of large genes and large genomic fragments.
| Contact Details: |
| 8081 Lougheed Highway |
| Burnaby |
| British Columbia |
| V5A 1W9 |
| Canada |
| Tel: | 604 415 7100 |
| Fax: | 604 415 7151 |
| Email: | info@chromos.com |
| WWW: | www.chromos.com/
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Recent Publications by Chromos Molecular Systems Incorporated: |  |
Chromosomal engineering.
Artificial chromosomes (ACs) are engineered chromosomes with defined... | 16th January, 2008
| Chromos Molecular Systems Inc., 8081 Lougheed Highway, Burnaby, BC, Canada
| Curr Opin Biotechnol. 2007 Oct;18(5):420-4. Epub 2007 Oct 30.
DOI Direct Link |
Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells.
OBJECTIVE: The transfer of mammalian artificial chromosomes (MACs) to... | 4th February, 2006
| Chromos Molecular Systems, Inc., British Columbia, Canada.
| Exp Hematol. 2005 Dec;33(12):1470-6.
DOI Direct Link |
Transfer and stable transgene expression of a mammalian artificial chromosome into bone marrow-derived human mesenchymal stem cells.
Mammalian artificial chromosomes (ACEs) transferred to autologous adult... | 5th October, 2005
| Chromos Molecular Systems Inc., Burnaby, British Columbia, Canada.
| Stem Cells. 2004;22(3):324-33.
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A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy.
Mammalian artificial chromosomes (MACs) provide a means to introduce large... | 21st December, 2004
| Chromos Molecular Systems, Inc., 8081 Lougheed Highway, Burnaby, BC,
| Nucleic Acids Res. 2004 Dec 7;32(21):e172.
DOI Direct Link |
Pronuclear microinjection of purified artificial chromosomes for generation of transgenic mice: pick-and-inject technique.
Mammalian artificial chromosomes (ACEs) transferred to autologous adult... | 23rd April, 2004
| Chromos Molecular Systems, Inc, Burnaby, British Columbia, Canada.
| Methods Mol Biol. 2004;240:227-42.
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→View more Chromos Molecular Systems Incorporated research publications. |
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