Phylonix

Phylonix is a Contract Research Organization providing in vivo zebrafish assays for drug discovery and screening. Our toxicologists, biochemists, developmental biologists, aquaculturists and molecular biologists can perform general, organ and cell specific toxicity studies, pathology, gene profiling, cellular activity and behavioral studies. Custom assays can be designed for high throughput quantitative microplate analysis or multi-parameter visual assessment

Contact Details: 100 Inman Street, Suite 300 Cambridge Massachusetts 02139 United States of America Tel: (617) 441-6700 Fax: (617) 441-6766 Email: info@phylonix.com WWW: www.phylonix.com/

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Recent Publications by Phylonix:
Nanosize delivery as an emerging platform for cancer therapy. Although monoclonal antibody (mAb) drugs targeting protein interactions...	20th January, 2009	Phylonix Pharmaceutical Company, Cambridge, Massachusetts, USA.	Cancer Biol Ther. 2008 Nov 8;7(11).
Zebrafish: a predictive model for assessing drug-induced toxicity. The zebrafish model organism is increasingly used for assessing drug...	8th October, 2008	Phylonix, 100 Inman	Drug Discov Today. 2008 May;13(9-10):394-401. Epub 2008 Apr 22. DOI Direct Link
Neurotoxicity assessment using zebrafish. INTRODUCTION: Transparency is a unique attribute of zebrafish that permits...	18th April, 2007	Phylonix Pharmaceuticals, Inc., 100 Inman St., Cambridge, MA 02139, USA.	J Pharmacol Toxicol Methods. 2007 Jan-Feb;55(1):103-12. DOI Direct Link
Human melanoma cells transplanted into zebrafish proliferate, migrate, produce melanin, form masses and stimulate angiogenesis in zebrafish. In this research, we optimized parameters for xenotransplanting WM-266-4,...	6th February, 2007	Phylonix Pharmaceuticals, Inc., 100 Inman Street, suite 300, Cambridge, MA	Angiogenesis. 2006;9(3):139-51. Epub 2006 Oct 19. DOI Direct Link
A zebrafish assay for identifying neuroprotectants in vivo. In this study, we developed an in vivo method to determine drug effects on...	9th November, 2006	Phylonix Pharmaceuticals, Inc., 100 Inman Street, Cambridge, MA 02139,	Neurotoxicol Teratol. 2006 Jul-Aug;28(4):509-16. Epub 2006 Jun 30. DOI Direct Link
→View more Phylonix research publications.

Phylonix Patents:
US Patent No.	Title
7482507	Methods of screening agents for activity using teleosts
7435870	Methods of screening agents for activity using teleosts
7408095	Methods for introducing heterologous cells into fish to determine if the heterologous cells contain cancer cells or a pathogen
7041276	Methods of screening agents for activity using teleosts
6761876	Methods for introducing helterologous cells into fish
→View more Phylonix patents.

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