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Cortex Pharmaceuticals

Cortex Pharmaceuticals Incorporated is a development stage enterprise that was organized in 1987 to engage in the discovery, development and commercialization of innovative pharmaceuticals for the treatment of neurodegenerative diseases and other neurological and psychiatric disorders. Since 1993, the primary effort at Cortex has been centered on developing products that affect the AMPA-type glutamate receptor, a complex of proteins that is involved in most "excitatory" communication between nerve cells in the human brain. Cortex is developing a family of chemical compounds, knownas Ampakines/(R)/, that enhance the activity of this receptor. Cortex believes that Ampakines hold promise for correcting deficits brought on by a variety of diseases and disorders that are known, or thought, to involve depressed functioning of pathways in the brain that use glutamate as a neurotransmitter.


Contact Details:
15231 Barranca Parkway
Irvine
CA
92618
United States of America
Tel:714 727 3157
Fax:714 727 3657
Email:info@cortexpharm.com
WWW:

www.cortexpharm.com/




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Recent Publications by Cortex Pharmaceuticals:

Randomized, double-blind, placebo-controlled international clinical trial of the Ampakine CX516 in elderly participants with mild cognitive impairment: a progress report.
This progress report briefly describes the rationale and study design for...
29th January, 2003
Cortex Pharmaceuticals, Inc., Irvine, CA 92618, USA. J Mol Neurosci. 2002 Aug-Oct;19(1-2):197-200.
Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein.
A critical issue concerning Alzheimer's disease is its selectivity, which...
20th June, 2000
Cortex Pharmaceuticals, Inc., Irvine, California 92618, USA. J Comp Neurol. 1998 Jul 20;397(1):139-47.

BioNews Results for Cortex Pharmaceuticals:

Valeant Announces Presentation of Retigabine Data at the 8th European Congress on Epileptology
Pharma Live:  Sep 17 2008 12:04AM Matching: cortex pharmaceuticals
Valeant Announces Presentation of Retigabine Data at the 8th European Congress on Epileptology
Genetic Engineering News:  Sep 15 2008 11:21PM Matching: cortex pharmaceuticals
CORTEX PHARMACEUTICALS INC Consensus Recommendation: STRONG BUY
Macro World Investor:  Sep 12 2008 5:14PM Matching: cortex pharmaceuticals
Rodman & Renshaw Changes EPS Estimate of CORTEX PHARMACEUTICALS INC: Current Recommendation is Market Outperfo
Calibre Macro World:  Sep 12 2008 5:31PM Matching: cortex pharmaceuticals
Rodman & Renshaw Changes EPS Estimate of CORTEX PHARMACEUTICALS INC: Current Recommendation is Market Outperfo
Macro World Investor:  Sep 12 2008 5:14PM Matching: cortex pharmaceuticals
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Cortex Pharmaceuticals Patents:

US Patent No.Title
6166008 Treatment of schizophrenia with ampakines and neuroleptics
5985871 Benzoxazine compounds for enhancing synaptic response
5736543 Benzoxazines for enhancing synaptic response
5650409 Benzoyl piperidines/pyrrolidines for enhancing synaptic response
5622981 Use of metabotropic receptor agonists in progressive neurodegenerative diseases

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