Recent Publications by Corvas International Incorporated: |
Antiparasitic agents.
Parasitic diseases predominantly affect the developing world because of... | 4th October, 2005
| Corvas International, 3030 Science Park Road, San Diego, California 92307,
| IDrugs. 1998 Dec;1(8):843-5.
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Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis.
Understanding the regulation of physiological processes requires detailed... | 25th June, 2003
| Department of Molecular Biology, Corvas International, 3030 Science Park
| Biochemistry. 2003 May 13;42(18):5395-402.
DOI Direct Link |
Inhibition of factor VIIa/tissue factor with nematode anticoagulant protein c2: from unique mechanism to a promising new clinical anticoagulant.
Recombinant nematode anticoagulant protein c2 (rNAPc2) is a potent (K(i) =... | 13th March, 2003
| Corvas International, Inc., San Diego, California 92121, USA.
| Trends Cardiovasc Med. 2002 Nov;12(8):325-31.
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Non-covalent thrombin inhibitors featuring P3-heterocycles with P1-bicyclic arginine surrogates.
Novel, potent, and highly selective classes of thrombin inhibitors were... | 12th March, 2003
| Department of Medicinal Chemistry, Corvas International, Inc., 3030
| Bioorg Med Chem Lett. 2002 Oct 21;12(20):2925-30.
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Non-covalent thrombin inhibitors featuring P(3)-heterocycles with P(1)-monocyclic arginine surrogates.
Investigations on P(2)-P(3)-heterocyclic dipeptide surrogates directed... | 3rd October, 2002
| Department of Medicinal Chemistry, Corvas International, Inc., 3030
| Bioorg Med Chem Lett. 2002 Apr 22;12(8):1203-8.
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Novel hydrazino-carbonyl-amino-methylated polystyrene (HCAM) resin methodology for the synthesis of P1-aldehyde protease inhibitor candidates.
[structure: see text] A new strategy for the synthesis of peptidyl and... | 24th June, 2000
| Department of Medicinal Chemistry, Corvas International, Inc., San Diego,
| Org Lett. 2000 Jan;2(1):19-22.
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Guanylpiperidine peptidomimetics: potent and selective bis-cation inhibitors of factor Xa.
A novel series of rigid P3-guanylpiperidine peptide mimics 3-14 was... | 24th June, 2000
| Corvas International, Inc., Department of Medicinal Chemistry, San Diego,
| Bioorg Med Chem Lett. 2000 Apr 17;10(8):745-9.
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