Recent Publications by Cubist Pharmaceuticals: |
Daptomycin for the treatment of enterococcal bacteraemia: results from the Cubicin Outcomes Registry and Experience (CORE).
Enterococcal infections are a common cause of nosocomial bloodstream... | 26th June, 2009
| Cubist Pharmaceuticals, Inc., 65 Hayden Avenue, Lexington, MA 02421, USA.
| Int J Antimicrob Agents. 2009 Jun;33(6):543-8. Epub 2009 Feb 6.
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The Pharmacokinetics and Buccal Mucosal Concentrations of a 15 mg/kg Total Dose of Liposomal Amphotericin B Either as a Single (15mg/kg) Dose, Weekly Dose (7.5mg/kg), or a Daily Dose (1mg/kg) in Peripheral Stem Cell Transplant Patients.
The pharmacokinetics and safety of extended interval dosing for... | 24th June, 2009
| College of Pharmacy, University of Arkansas for Medical Sciences, Little
| Antimicrob Agents Chemother. 2009 Jun 22.
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Chapter 20. Biosynthesis and genetic engineering of lipopeptides in Streptomyces roseosporus.
Daptomycin is an acidic cyclic lipopeptide antibiotic approved for... | 24th June, 2009
| Cubist Pharmaceuticals Inc, Lexington, Massachusetts, USA.
| Methods Enzymol. 2009;458:511-31.
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Daptomycin Rapidly Penetrates a Staphylococcus epidermidis Biofilm.
Fluorescently-tagged daptomycin accessed the interior of Staphylococcus... | 20th May, 2009
| Center for Biofilm Engineering and Department of Chemical and Biological
| Antimicrob Agents Chemother. 2009 May 18.
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The efficacy and safety of daptomycin vs. vancomycin for the treatment of cellulitis and erysipelas.
BACKGROUND: Results from previous trials suggest that daptomycin may... | 12th May, 2009
| Clinical Research, Cubist Pharmaceuticals, Lexington, MA 02421, USA.
| Int J Clin Pract. 2009 Mar;63(3):368-75.
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A pilot study of high-dose short duration daptomycin for the treatment of patients with complicated skin and skin structure infections caused by gram-positive bacteria.
BACKGROUND: Methicillin-susceptible and -resistant (MRSA) Staphylococcus... | 8th May, 2009
| Cubist Pharmaceuticals, Inc., Lexington, MA 02421, USA.
| Int J Clin Pract. 2008 Sep;62(9):1455-64. Epub 2008 Jul 25.
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Daptomycin: mechanisms of action and resistance, and biosynthetic engineering.
Daptomycin is a lipopeptide antibiotic used clinically to treat infections... | 24th March, 2009
| Discovery Biology, Cubist Pharmaceuticals, Inc., 65 Hayden Avenue,
| Curr Opin Chem Biol. 2009 Apr;13(2):144-51. Epub 2009 Mar 19.
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Renaissance in antibacterial discovery from actinomycetes.
The soil actinomycetes have been important sources of antibiotics, but... | 31st January, 2009
| Drug Discovery and Evaluation, Cubist Pharmaceuticals, Inc., 65 Hayden
| Curr Opin Pharmacol. 2008 Oct;8(5):557-63. Epub 2008 Jun 3.
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Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus.
Genetic engineering has been applied to reprogramme non-ribosomal peptide... | 10th October, 2008
| Cubist Pharmaceuticals Inc., 65 Hayden Avenue, Lexington, MA 02421, USA.
| Microbiology. 2008 Sep;154(Pt 9):2872-80.
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Outpatient parenteral antibiotic therapy with daptomycin: insights from a patient registry.
AIM: To compare and contrast the characteristics and clinical outcomes of... | 1st October, 2008
| Cubist Pharmaceuticals, Inc., Lexington, MA 02421, USA.
| Int J Clin Pract. 2008 Aug;62(8):1183-7.
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Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin.
Daptomycin is a clinically important antibiotic approved for the treatment... | 23rd September, 2008
| Cubist Pharmaceuticals, Inc., 65 Hayden Avenue, Lexington, Massachusetts
| Curr Top Med Chem. 2008;8(8):618-38.
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Effects of prior effective therapy on the efficacy of daptomycin and ceftriaxone for the treatment of community-acquired pneumonia.
OBJECTIVE: We sought to compare daptomycin with ceftriaxone for the... | 29th July, 2008
| Cubist Pharmaceuticals, Lexington, Massachusetts 02421, USA.
| Clin Infect Dis. 2008 Apr 15;46(8):1142-51.
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Daptomycin exerts bactericidal activity without lysis of Staphylococcus aureus.
The ability of daptomycin to produce bactericidal activity against... | 17th July, 2008
| Cubist Pharmaceuticals, Inc., 65 Hayden Avenue, Lexington, MA 02421, USA.
| Antimicrob Agents Chemother. 2008 Jun;52(6):2223-5. Epub 2008 Mar 31.
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Treatment challenges in the management of complicated skin and soft-tissue infections.
Complicated skin and soft-tissue infections (cSSTIs) are a significant... | 16th May, 2008
| Cubist Pharmaceuticals, Inc., Lexington, MA and Harvard Medical School,
| Clin Microbiol Infect. 2008 Mar;14 Suppl 2:17-25.
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Treatment of staphylococcal infections with cyclic lipopeptides.
Daptomycin is the first of a new class of antibiotics, the cyclic... | 16th May, 2008
| Cubist Pharmaceuticals, Inc., Lexington, MA and Harvard Medical School,
| Clin Microbiol Infect. 2008 Mar;14 Suppl 2:10-6.
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