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CuraGen

CuraGen Corporation (Nasdaq: CRGN) is a biopharmaceutical company dedicated to improving the lives of patients by developing novel pharmaceutical products that address unmet medical needs. CuraGen’s deep understanding of the human genome has enabled us to gain greater insight into the molecular basis of disease. The Company's therapeutics are based on novel drug targets that are believed to play a role in proven mechanisms underlying disease. CuraGen has translated this understanding into a pipeline of protein, antibody, and small molecule drugs in the areas of oncology, inflammatory diseases, and diabetes. The Company’s strategy remains focused on advancing its pipeline of promising therapeutics through clinical and preclinical development. History CuraGen was founded when the massive undertaking to sequence the human genome was just beginning. The Company's strategy was based on discovering novel ways to combat disease through an understanding of how genes and their resulting proteins function within the human genome. CuraGen developed an integrated genomics, proteomics, and bioinformatics technology platform that was used to analyze the human genome, disease models, and therapeutic candidates. This approach led to the identification of disease-related genes and therapeutic targets with the subsequent development of novel pharmaceutical products. Today, CuraGen remains one of the leading genomics-based pharmaceutical companies in the industry with a pipeline of protein, antibody, and small molecule therapeutics. The Company is headquartered in Branford, CT.


Contact Details:
322 East Main Street
Branford
CT
06405
United States of America
Tel:(888) 436-6642 or (203) 481-1104
Fax:(203) 483-2552
Email:info@curagen.com
WWW:

www.curagen.com/




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Recent Publications by CuraGen:

Effects of pH and arginine on the solubility and stability of a therapeutic protein (Fibroblast Growth Factor 20): relationship between solubility and stability.
The purpose of this study was to dramatically enhance the solubility (>...
22nd July, 2009
Biopharmaceutical Process Sciences, CuraGen Coporation, 322 East Main Curr Pharm Biotechnol. 2009 Sep;10(6):609-25. Epub 2009 Sep 1.
Pharmacologically enhanced expression of GPNMB increases the sensitivity of melanoma cells to the CR011-vcMMAE antibody-drug conjugate.
GPNMB is a melanoma-associated glycoprotein that is targeted by the...
16th July, 2009
CuraGen Corporation, Branford, CT 06405, USA. Mol Oncol. 2008 Jun;2(1):81-93. Epub 2008 Feb 16.
DOI Direct Link
Mapping of solution components, pH changes, protein stability and the elimination of protein precipitation during freeze-thawing of fibroblast growth factor 20.
This study discusses the effect of key factors like containers, buffers...
10th June, 2009
Biopharmaceutical Process Sciences, CuraGen Corporation, 322 East Main Int J Pharm. 2009 Aug 13;378(1-2):122-35. Epub 2009 Jun 6.
DOI Direct Link
A phase I study of CR002, a fully-human monoclonal antibody against platelet-derived growth factor-D.
OBJECTIVE: To investigate the safety, pharmacokinetics (PK), binding...
19th August, 2008
CuraGen Corporation, Branford, CT 06405, USA. Int J Clin Pharmacol Ther. 2008 May;46(5):236-44.
Single-Dose Prevention or Short-Term Treatment with Fibroblast Growth Factor-20 (CG53135-05)Reduces the Severity and Duration of Oral Mucositis.
Oral mucositis (OM) is a treatment-limiting condition associated with...
17th July, 2008
CuraGen Corporation, Branford, CT. Support Cancer Ther. 2005 Jan 1;2(2):122-7.
DOI Direct Link

View more CuraGen research publications.

Press Releases on CuraGen:

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CuraGen Announces Expansion of CR011-vcMMAE Phase II Trial in Advanced Breast Cancer 17th June, 2009 CuraGen Corporation
- 12 week progression free rate supports advancement into second stage of Simon 2-Stage designed trial - BRANFORD, Conn., June 17 /PRNewswire-FirstCall/ -- CuraGen Corporation (Nasdaq: CRGN)
CuraGen Updates CR011-vcMMAE Data at ASCO 2nd June, 2009 CuraGen Corporation
- Activity Demonstrated in Advanced Breast Cancer and Melanoma - - Conference call to be hosted Wednesday, June 3, 2009 at 11:00am ET to discuss results - BRANFORD, Conn., June 2 /PRNewswire
CuraGen to Present CR011-vcMMAE Data at ASCO 28th May, 2009 CuraGen Corporation
- Update from Advanced Breast Cancer and Melanoma Studies - Conference Call to be Hosted on Wednesday, June 3, 2009 at 11:00 am BRANFORD, Conn., May 28 /PRNewswire-FirstCall/ -- CuraGen
/C O R R E C T I O N -- CuraGen Corporation/ 23rd April, 2009 CuraGen Corporation
In the news release, CuraGen (Nasdaq: CRGN) Reports First Quarter 2009 Financial Results, issued April 23, 2009 by CuraGen Corporation over PR Newswire, the CONDENSED STATEMENTS OF OPERATIONS table
CuraGen Reports First Quarter 2009 Financial Results 23rd April, 2009 CuraGen Corporation
BRANFORD, Conn., April 23 /PRNewswire-FirstCall/ -- CuraGen Corporation (Nasdaq: CRGN), today reported its financial results for the first quarter of 2009. During the three month period ended March

BioNews Results for CuraGen:

Bio-IT World Weekly Update: Nov 10
Bio-IT World:  Nov 12 2009 1:57PM Matching: curagen
Celldex Therapeutics Q3 net loss narrows
Therapeutics Daily:  Nov 6 2009 12:18PM Matching: curagen
Celldex Therapeutics Reports Third Quarter and Nine Month 2009 Financial Results
Therapeutics Daily:  Nov 4 2009 8:19PM Matching: curagen
Celldex Therapeutics Reports Third Quarter and Nine Month 2009 Financial Results
Genetic Engineering News:  Nov 4 2009 1:48PM Matching: curagen
Celldex announces third quarter and nine-month period results; acquires a net loss of $7.2 million
News-Medical.Net:  Nov 4 2009 12:54PM Matching: curagen
Promote your company here: BioNewsCast - Press Release Distribution

View more CuraGen news.

CuraGen Clinical Trials:

A Phase II Controlled Trial of Velafermin for Prevention of Oral Mucositis

CuraGen Patents:

US Patent No.Title
6537554 Nucleotide sequences and amino acid sequences of secreted proteins involved in angiogenesis
6750012 Method of identifying a psychotropic agent using differential gene expression
6753314 Protein-protein complexes and methods of using same
6822140 Compositions and methods for fumonisin detoxification
6852845 Method of identifying toxic agents using NSAID-induced differential gene expression in liver

View more CuraGen patents.

CuraGen (CRGN) Financial information Links from Barchart

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