AP Pharma

A.P. Pharma, Inc. (NASDAQ Global Market: APPA) is a specialty pharmaceutical company focused on the development and commercialization of innovative medical treatments utilizing its proprietary polymer-based drug delivery systems. We are focused on developing pharmaceutical products using our proprietary BiochronomerTM polymer-based drug delivery technology. Our product development philosophy is based on incorporating approved therapeutics into our proprietary bioerodible drug delivery technology to create controlled release pharmaceuticals to improve treatments for diseases or conditions. Our lead product candidate, APF530, is currently in a pivotal Phase III clinical trial for the prevention of acute and delayed onset chemotherapy-induced nausea and vomiting, or CINV. Our primary focus is to advance our proprietary Biochronomer technology, consisting of bioerodible polymers designed to release drugs over a defined period. We have completed over 100 in vivo and in vitro studies demonstrating that our Biochronomer technology is potentially applicable to a range of therapeutic areas, including pain management, prevention of nausea and vomiting, control of inflammation and treatment of ophthalmic diseases. We have also completed comprehensive animal and human toxicology studies that have established that our Biochronomer polymers are safe and well tolerated. Furthermore, our Biochronomer technology can be designed to deliver drugs over periods varying from days to several months.

Contact Details: 123 Saginaw Drive Redwood City 94063 Tel: 650-366-2626 Fax: Email: jobs@appharma.com WWW: www.appharma.com/

Recent Publications by AP Pharma:
Poly(ortho esters)--from concept to reality. The development of poly(ortho esters) dates back to the early 1970s, and...	23rd February, 2005	AP Pharma, 123 Saginaw Drive, Redwood City, California 94063, USA.	Biomacromolecules. 2004 Sep-Oct;5(5):1625-32. DOI Direct Link
Design of an injectable system based on bioerodible polyanhydride microspheres for sustained drug delivery. The fabrication, morphological characterization, and drug release kinetics...	23rd April, 2003	AP Pharma, Redwood City, CA 94063, USA.	Biomaterials. 2002 Nov;23(22):4405-12.

BioNews Results for AP Pharma:
APDCA to recommend state govt to procure medicines from companies within AP	PharmaBiz:  Aug 29 2008 5:00AM Matching: ap pharma
Belgian drug maker UCB to shed 2,000 staff worldwide as revenues slip as patents expire	Canadian Business Magazine:  Aug 28 2008 12:30PM Matching: ap pharma
Belgian drug maker UCB to shed 2,000 staff worldwide as revenue slip on expiry of patents	Canadian Business Magazine:  Aug 28 2008 12:15PM Matching: ap pharma
Belgian drug maker UCB to shed 2,000 jobs globally	PR inside:  Aug 28 2008 11:55AM Matching: ap pharma
Bal Phrama to commission Uttarakhand facility shortly	Express Pharma:  Aug 26 2008 11:16PM Matching: ap pharma
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AP Pharma Patents:
US Patent No.	Title
6822000	Bioerodible poly (orthoesters) from dioxolane-based diketene acetals
6790458	Pharmaceutical compositions using semi-solid delivery vehicle
6590059	Bioerodible polyorthoesters from dioxolane-based diketene acetals
6524606	Bioerodible polyorthoesters containing amine groups

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