Lpath

Lpath, Inc., headquartered in San Diego, California, is a theranostics company focused on bioactive signaling lipids as targets for treating and diagnosing important human diseases. Lpath's lead product candidate, Sphingomab™, is a monoclonal antibody (mAb) against a validated cancer target, sphingosine-1-phosphate (S1P), and has demonstrated compelling results against six different forms of solid-tumor and blood-borne cancers in pre-clinical studies. Like Avastin® (Genentech's enormously successful cancer drug), Sphingomab™ is anti- angiogenic, but Sphingomab™ has other mechanisms of action that may prove advantageous in the clinical setting. As such, although Genentech pioneered the anti-angiogenesis approach to treating cancer, Lpath believes Sphingomab™ may prove to be the next generation of anti- angiogenesis-based therapeutics.

Contact Details: 6335 Ferris Square Suite A San Diego CA 92121 United States of America Tel: 858-678-0800 Fax: 858-678-0900 Email: info@lpath.com WWW: www.lpath.com/

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Recent Publications by Lpath:
The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. The pleiotropic signaling lipid sphingosine-1-phosphate (S1P) plays...	10th October, 2009	Lpath Inc., 6335 Ferris Square, Suite A, San Diego, CA 92121, USA.	Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17717-22. Epub 2009 Oct 7. DOI Direct Link
Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye. Sphingosine-1-phosphate (S1P) is a pleiotropic lysolipid that has recently...	17th December, 2008	Lpath	Exp Eye Res. 2008 Oct;87(4):367-75. Epub 2008 Jul 18. DOI Direct Link

Press Releases on Lpath:
Reportlinker Adds Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment	26th October, 2009	Reportlinker	-- A focus on "engineered" antibodies Monoclonal Antibodies: Pipeline Analysis and Competitive Assessment reviews the broad drug development effort that is focused on bringing
Reportlinker Adds Immunotherapies and Vaccines for Nontraditional Indications	26th October, 2009	Reportlinker	NEW YORK, Oct. 26 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Reportlinker Adds Immunotherapies and Vaccines for Nontraditional
Biocept, Inc. Announces Two New Director Appointments	1st July, 2009	Biocept, Inc.	SAN DIEGO, July 1 /PRNewswire/ -- Biocept, Inc. ("Biocept"), an emerging leader in biotechnology, announced today the appointment of Daniel H. Petree and M. Faye Wilson as Directors. "

BioNews Results for Lpath:
Lpath, Inc. - Pharmaceuticals & Healthcare - Deals and Alliances Profile - new report released	PR inside:  Nov 13 2009 4:34PM Matching: lpath
Lpath to present clinical results of iSONEP drug in wet-AMD patients	News-Medical.Net:  Oct 24 2009 9:57AM Matching: lpath
Lpath, Inc. to Present at the 2009 BIOCOM Investor Conference	BioSpace:  Oct 23 2009 5:49PM Matching: lpath
Lpath Receives Grants From the National Institutes of Health and Publishes Key Paper in the Proceedings of the National Academy of Sciences	Individual.com:  Oct 20 2009 12:25PM Matching: lpath
Lpath's Phase I wet-AMD trial meets endpoint	Therapeutics Daily:  Oct 12 2009 1:32PM Matching: lpath
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