Diacrin Incorporated

Diacrin is developing transplantable cells for the treatment of human diseases which are characterized by cell dysfunction or cell death and for which current therapies are either inadequate or nonexistent. Products under development for the treatment of neurological disorders include: NeuroCell(TM)-PD for Parkinson's disease and NeuroCell(TM)-HD for Huntington's disease, both of which are being developed in a joint venture with Genzyme Corporation ("Genzyme"), NeuroCell(TM)-FE for focal epilepsy, porcine neural cells for stroke and intractable pain and spinal cord cells for spinal cord injury. Also under development are hepatocytes for acute liver failure and for cirrhosis, myoblasts for cardiac disease and retinal epithelial cells for macular degeneration.

Contact Details: Building 96 13th Street Charlestown MA 02129 United States of America Tel: 617 242 9100 Fax: 617 242 0070 Email: clinicalinfo@diacrin.com WWW: www.diacrin.com/

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Recent Publications by Diacrin Incorporated:
An overview of myoblast transplantation for myocardial regeneration. Regenerative medicine represents a new frontier in treatment of disease,...	16th September, 2005	Diacrin, Inc., Charlestown, MA, USA.	Am Heart Hosp J. 2005 Summer;3(3):146-52.
A novel monoclonal antibody inhibits the immune response of human cells against porcine cells: identification of a porcine antigen homologous to CD58. BACKGROUND: Human CD58 is an adhesion molecule that interacts with CD2 on...	1st July, 2004	Diacrin, Inc. Charlestown, MA, USA.	Transplantation. 2004 Apr 27;77(8):1288-94.
Long-term survival of fetal porcine lateral ganglionic eminence cells in the hippocampus of rats. Embryonic porcine brain tissue from the lateral ganglionic eminence was...	20th June, 2000	Diacrin, Inc., Department of Cell Transplantation, Charlestown Navy Yard,	J Neurosci Res. 1999 Jun 15;56(6):581-94.

Diacrin Incorporated Patents:
US Patent No.	Title
6821779	Methods for storing neural cells
6204053	Porcine cortical cells and their use in treatment of neurological deficits due to neurodegenerative diseases
6140116	Isolated and modified porcine cerebral cortical cells
6096537	Cells with multiple altered epitopes on a surface antigen for use in transplantation
5961972	Isolated porcine pancreatic cells for use in treatment of diseases characterized by insufficient insulin activity
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