Alexion Pharmaceuticals Incorporated

Alexion Pharmaceuticals Incorporated is a biopharmaceutical company engaged in the research and development of proprietary immunoregulatory compounds for the treatment of autoimmune and cardiovascular diseases. The Company is developing C5 Complement Inhibitors and Apogens, two classes of potential therapeutic compounds designed to selectively target specific disease-causing segments of the immune system.

Contact Details: 352 Knotter Drive Cheshire 06410 United States of America Tel: 203 272 2596 Fax: 203 772 3655 Email: alexion.europe@alxn.com WWW: www.alexionpharm.com/

Recent Publications by Alexion Pharmaceuticals Incorporated:
C5 blockade with conventional immunosuppression induces long-term graft survival in presensitized recipients. We explored whether a functionally blocking anti-C5 monoclonal antibody...	4th July, 2008	Alexion Pharmaceuticals, Inc., Cheshire, CT, USA.	Am J Transplant. 2008 Jun;8(6):1129-42. Epub 2008 Apr 29. DOI Direct Link
Characterization of cartilage from H-transferase transgenic pigs. Cartilage engineering is the object of intense research as a result of...	25th June, 2008	Department of Molecular Sciences, Alexion Pharmaceuticals, Inc, Cheshire,	Transplant Proc. 2008 Mar;40(2):554-6. DOI Direct Link
Mass spectrometry and HPLC with fluorescent detection-based orthogonal approaches to characterize N-linked oligosaccharides of recombinant monoclonal antibodies. A number of HPLC and mass spectrometric techniques are used to...	5th June, 2008	Alexion Pharmaceuticals, Cheshire, CT, USA.	Methods Mol Biol. 2008;446:347-61. DOI Direct Link
Comparability and monitoring immunogenic N-linked oligosaccharides from recombinant monoclonal antibodies from two different cell lines using HPLC with fluorescence detection and mass spectrometry. One of the most important structural features of recombinant monoclonal...	5th June, 2008	Alexion Pharmaceuticals, Cheshire, CT, USA.	Methods Mol Biol. 2008;446:333-46. DOI Direct Link
Monitoring glycosylation of therapeutic glycoproteins for consistency by HPLC using highly fluorescent anthranilic acid (AA) tag. Majority of protein drugs in development today are glycoproteins e.g....	5th June, 2008	Alexion Pharmaceuticals, Cheshire, CT, USA.	Methods Mol Biol. 2008;446:317-31. DOI Direct Link
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BioNews Results for Alexion Pharmaceuticals Incorporated:
Connecticut Technology Council Announces UHY LLP Tech Top 40 Winners	KRON4:  Oct 4 2008 6:17AM Matching: alexion pharmaceuticals
Connecticut Technology Council Announces UHY LLP Tech Top 40 Winners	KSLA:  Oct 4 2008 12:09AM Matching: alexion pharmaceuticals
Connecticut Technology Council Announces UHY LLP Tech Top 40 Winners	Montana's News Station:  Oct 3 2008 4:45PM Matching: alexion pharmaceuticals
Alexion's Soliris receives 'Nobel' equivalent	Checkbiotech:  Oct 2 2008 4:00PM Matching: alexion pharmaceuticals
A Top BioMarin Drug Heads Overseas	Checkbiotech:  Oct 1 2008 3:12PM Matching: alexion pharmaceuticals
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Alexion Pharmaceuticals Incorporated Patents:
US Patent No.	Title
7427665	Chronic lymphocytic leukemia cell line
6355245	C5-specific antibodies for the treatment of inflammatory diseases
6338820	Apparatus for performing assays at reaction sites
6074642	Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
6040428	Porcine E-selectin
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