DNAX Research Institute

DNAX is organized around five departments–immunology, oncology, genomics, protein and antibody engineering, and experimental pathology and pharmacology. Its core competencies and depth of intellectual property lie primarily in two therapeutic areas: immunology and oncology. The DNAX management structure, departmental organization and project teams are coordinated and integrated to provide the best possible environment to pursue research in these two focus areas, taking advantage of new or existing scientific resources in-house, such as FACS, proteomics and gene-targeting technologies. Complementary resources at Schering-Plough Research Institute are available for collaborative studies.

Contact Details: 901 California Avenue Palo Alto CA 94304 United States of America Tel: 415 852 9196 Fax: 415 852 9196 Email: WWW: www.dnasrch.com/

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Recent Publications by DNAX Research Institute:
Regulatory T cells and Toll-like receptors: what is the missing link? Toll-like receptors (TLRs) are critical sensors for microbial products and...	23rd June, 2009	Schering-Plough Biopharma (formerly DNAX Research Institute), Palo Alto,	Int Immunopharmacol. 2009 May;9(5):528-33. Epub 2009 Feb 1. DOI Direct Link
Cytokines that regulate autoimmunity. Recent advances have revealed new insights in cytokine regulation of...	20th February, 2009	Discovery Research, Schering-Plough Biopharma (formerly DNAX Research	Curr Opin Immunol. 2008 Dec;20(6):663-8. Epub 2008 Oct 17. DOI Direct Link
Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. This unit describes a general method for immunoenzymetric assay of mouse...	17th July, 2008	DNAX Research Institute, Palo Alto, California, USA.	Curr Protoc Immunol. 2001 May;Chapter 6:Unit 6.20. DOI Direct Link
Pivotal roles of CD4+ effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors. Glucocorticoid-induced TNF receptor family related protein (GITR) is a...	6th February, 2008	Discovery Research, Schering-Plough Biopharma (Formerly DNAX Research	J Immunol. 2007 Dec 1;179(11):7365-75.
Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. The cytokine interleukin-10 (IL-10) is an important regulator of immune...	25th April, 2007	DNAX Research Institute, Palo Alto, CA 94304, USA.	J Interferon Cytokine Res. 2006 May;26(5):281-90. DOI Direct Link
→View more DNAX Research Institute research publications.

BioNews Results for DNAX Research Institute:
Potential treatment for Huntington's disease	Science Daily:  Nov 16 2009 12:14AM Matching: research institute
Research from University of Tubingen, Hertie Institute for Clinical Brain Research provides new data on geneti	NewsRX:  Nov 15 2009 12:06PM Matching: research institute
Researchers Find Potential Treatment for Huntington's Disease	Newswise:  Nov 15 2009 8:19PM Matching: research institute
Researchers find potential treatment for Huntington's disease	Genetic Engineering News:  Nov 15 2009 8:47PM Matching: research institute
Researchers find potential treatment for Huntington's disease	Genetic Engineering News:  Nov 15 2009 7:22PM Matching: research institute
Promote your company here: BioNewsCast - Press Release Distribution	→View more DNAX Research Institute news.

DNAX Research Institute Patents:
US Patent No.	Title
4798789	cDNA clones coding for polypeptides exhibiting murine interleukin-2 activity
4758511	CDNA clones coding for polypeptides exhibiting IGE binding factor activity
4749685	Immunosuppressive peptides
4695542	cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
4690893	Hybridoma cell lines producing monoclonal antibodies which specifically bind to mouse interleukin-2
→View more DNAX Research Institute patents.

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