Recent Publications by MitoSciences: |
Novel antibody-based strategies for the rapid diagnosis of mitochondrial disease and dysfunction.
We are developing rapid immunoassays to measure the protein levels,... | 5th November, 2009
| MitoSciences, Inc., 1850 Millrace Dr., Eugene, OR 97403, USA.
| Int J Biochem Cell Biol. 2009 Oct;41(10):2081-8. Epub 2009 May 19.
DOI Direct Link |
Isolated deficiencies of OXPHOS complexes I and IV are identified accurately and quickly by simple enzyme activity immunocapture assays.
OXPHOS deficits are associated with most reported cases of inherited,... | 29th July, 2009
| MitoSciences, Inc. Eugene, OR 97403, USA.
| Biochim Biophys Acta. 2009 May;1787(5):533-8. Epub 2008 Nov 10.
DOI Direct Link |
Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis.
Drug-induced mitochondrial toxicity can occur as a result of inhibition of... | 1st April, 2009
| MitoSciences Inc.,
| J Immunol Methods. 2009 Mar 31;343(1):1-12. Epub 2009 Jan 17.
DOI Direct Link |
Screening for the metabolic basis of neurodegeneration: developing a focused proteomic approach.
Metabolism is controlled by a complex system of transcriptional events and... | 8th January, 2009
| Mitosciences Inc, Eugene, OR, USA.
| Ann N Y Acad Sci. 2008 Dec;1147:348-57.
DOI Direct Link |
Monitoring oxidative and nitrative modification of cellular proteins; a paradigm for identifying key disease related markers of oxidative stress.
High levels of free radicals produced by the mitochondrial respiratory... | 30th December, 2008
| Mitosciences
| Adv Drug Deliv Rev. 2008 Oct-Nov;60(13-14):1497-503. Epub 2008 Jul 4.
DOI Direct Link |
Lateral-flow immunoassay for the frataxin protein in Friedreich's ataxia patients and carriers.
Friedreich's Ataxia (FA) is an inherited neurodegenerative disease caused... | 15th August, 2008
| MitoSciences, Inc., Research and Development, 1850 Millrace Drive, Suite
| Mol Genet Metab. 2008 Aug;94(4):491-7. Epub 2008 May 15.
DOI Direct Link |
Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount.
COX (cytochrome c oxidase) deficiency is one of the main causes of genetic... | 24th January, 2008
| Mitosciences Inc., Eugene, OR 97403-2095, USA.
| Biotechnol Appl Biochem. 2007 Dec;48(Pt 4):167-78.
DOI Direct Link |
Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration.
Mitochondrial impairment is increasingly implicated in the etiology of... | 19th October, 2007
| MitoSciences, Inc., 1850 Millrace Drive, Eugene, OR 97403, USA.
| Toxicol Appl Pharmacol. 2007 Sep 15;223(3):277-87. Epub 2007 Jun 21.
DOI Direct Link |
Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays.
Mitochondrial dysfunction has been shown to be a pharmacotoxicological... | 26th September, 2007
| MitoSciences Inc, 1850 Millrace Drive, Eugene, OR 97403, USA.
| Toxicol In Vitro. 2007 Aug;21(5):902-11. Epub 2007 Jan 20.
DOI Direct Link |
