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Alfacell Corporation

Alfacell Corporation is a biopharmaceutical company primarily engaged in the discovery and development of a new class of anti-cancer drugs from amphibian ribonucleases ("RNases"). RNases degrade ribonucleic acids ("RNA") causing an interruption in protein synthesis resulting in inhibition of cell growth and induction of apoptosis (programmed cell death). The Company's first product under development is ONCONASE(R) which targets solid tumors, most of which are known to become resistant to other chemotherapeutic drugs.


Contact Details:
225 Belleville Avenue
Bloomfield
07003
United States of America
Tel:973 748 8082
Fax:973 748 1355
Email:info@alfacell.com
WWW:

www.alfacell.com/




Recent Publications by Alfacell Corporation:

Effect of Onconase on double-stranded RNA in vitro.
Onconase is a cytotoxic ribonuclease which targets tumor cells in vivo and...
3rd July, 2009
Alfacell Corporation, Somerset, New Jersey 08873, USA. Anticancer Res. 2009 Apr;29(4):1067-71.
Onconase and amphinase, the antitumor ribonucleases from Rana pipiens oocytes.
Rana pipiens oocytes contain two homologues of pancreatic ribonuclease A...
28th October, 2008
Alfacell Corporation, 300 Atrium Drive, Somerset, NJ 08873, USA. Curr Pharm Biotechnol. 2008 Jun;9(3):215-25.
Onconase, an anti-tumor ribonuclease suppresses intracellular oxidative stress.
Onconase (ONC), an antitumor ribonuclease from oocytes of a frog Rana...
6th December, 2007
Alfacell Corporation, Int J Oncol. 2007 Sep;31(3):663-9.
Tamoxifen and trifluoroperazine (Stelazine) potentiate cytostatic/cytotoxic effects of P-30 protein, a novel protein possessing anti-tumor activity.
P-30 protein, a novel protein isolated in our laboratory from fertilized...
1st June, 2000
Alfacell Corporation, Bloomfield, New Jersey 07003. Cell Tissue Kinet. 1990 May;23(3):237-46.

Press Releases on Alfacell Corporation:

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Alfacell Provides Shareholder Update 19th June, 2009 Alfacell Corporation
SOMERSET, N.J., June 19 /PRNewswire-FirstCall/ -- Dear Shareholder, I am grateful to have this opportunity to share with you important developments taking place at this critical juncture in our
Alfacell Announces Receipt of NASDAQ Panel Decision 5th January, 2009 Alfacell Corporation
SOMERSET, N.J., Jan. 5 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL) today announced that it received notification on January 2, 2009 that the NASDAQ Listing Qualifications Panel has
Alfacell Provides ONCONASE(R) NDA Submission Update 5th December, 2008 Alfacell Corporation
SOMERSET, N.J., Dec. 5 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL) today reported that the U.S. Food and Drug Administration (FDA) has scheduled a pre-NDA meeting date at the end of
Alfacell Receives Going Concern Audit Opinion 23rd October, 2008 Alfacell Corporation
SOMERSET, N.J., Oct. 23 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL) today announced that its Annual Report on Form 10-K for the fiscal year ended July 31, 2008, filed with the
Alfacell Reports Fiscal Fourth Quarter and Full Year 2008 Financial Results 14th October, 2008 Alfacell Corporation
SOMERSET, N.J., Oct. 14 /PRNewswire-FirstCall/ -- Alfacell Corporation (Nasdaq: ACEL) today reported its financial results for the fourth quarter and fiscal year ended July 31, 2008. The company

Alfacell Corporation Clinical Trials:

ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen

Alfacell Corporation Patents:

US Patent No.Title
7585655 Nucleic acid encoding a fusion protein incorporating a cysteinized ribonuclease
5529775 Compositions comprising ONCONASE(.TM.) and cisplatin, melphalan, or doxorubicin HCl
5540925 Compositions comprising ONCONASE (TM) and STELAZINE (TM) or TAMOXIFEN (TM)
5559212 Frog embryo and egg-derived tumor cell anti-proliferation protein
5595734 Compositions comprising ONCONASE (tm) and lovastatin

View more Alfacell Corporation patents.

Alfacell Corporation (ACEL) Financial information Links from Barchart

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